WEL Research Institute

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Title DOI
https://doi.org/10.1038/nrgastro.2017.75 Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics
https://doi.org/10.1073/pnas.1219451110 Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
https://doi.org/10.1016/j.tcb.2018.12.001 EMT Transition States during Tumor Progression and Metastasis
https://doi.org/10.1136/gutjnl-2021-326789 Gut microbiome and health: mechanistic insights
https://doi.org/10.1038/s41591-019-0495-2 Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study
https://doi.org/10.1038/s41588-021-00913-z Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
https://doi.org/10.1038/nm.4236 A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice
https://doi.org/10.1136/gutjnl-2014-308778 Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology
https://doi.org/10.1136/gutjnl-2020-322260 Mucus barrier, mucins and gut microbiota: the expected slimy partners?
https://doi.org/10.1038/s41586-018-0040-3 Identification of the tumour transition states occurring during EMT
https://doi.org/10.1136/gutjnl-2018-316723 Human gut microbiome: hopes, threats and promises
https://doi.org/10.1126/science.aau0964 Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches
https://doi.org/10.1038/s41575-022-00631-9 Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms
https://doi.org/10.3389/fmicb.2017.01765 Next-Generation Beneficial Microbes: The Case of Akkermansia muciniphila
https://doi.org/10.1038/nrmicro.2017.26 Oxidative stress, protein damage and repair in bacteria
https://doi.org/10.1073/pnas.1415174111 Intestinal permeability, gut-bacterial dysbiosis, and behavioral markers of alcohol-dependence severity
https://doi.org/10.1038/nrc3597 Unravelling cancer stem cell potential
https://doi.org/10.1016/j.cmet.2015.07.026 Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling
https://doi.org/10.1038/nnano.2017.45 Imaging modes of atomic force microscopy for application in molecular and cell biology
https://doi.org/10.1146/annurev-pathol-012615-044438 Cancer Stem Cells: Basic Concepts and Therapeutic Implications
https://doi.org/10.1016/j.cell.2021.12.018 Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches
https://doi.org/10.1038/srep16643 Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice
https://doi.org/10.1038/ctg.2016.54 Human Intestinal Barrier Function in Health and Disease
https://doi.org/10.1038/nature11344 Defining the mode of tumour growth by clonal analysis
https://doi.org/10.1158/0008-5472.can-12-0569 Tryptophan Catabolism in Cancer: Beyond IDO and Tryptophan Depletion
https://doi.org/10.1038/nature13305 SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma
https://doi.org/10.1038/s41467-020-18319-6 Molecular interaction and inhibition of SARS-CoV-2 binding to the ACE2 receptor
https://doi.org/10.1038/nature22969 Fine-mapping inflammatory bowel disease loci to single-variant resolution
https://doi.org/10.1038/s41380-020-00925-x Diet and depression: exploring the biological mechanisms of action
https://doi.org/10.1152/ajpgi.00048.2015 Homeostasis of the gut barrier and potential biomarkers
https://doi.org/10.1038/ismej.2014.45 Microbiome of prebiotic-treated mice reveals novel targets involved in host response during obesity
https://doi.org/10.1016/j.stem.2018.11.011 Phenotypic Plasticity: Driver of Cancer Initiation, Progression, and Therapy Resistance
https://doi.org/10.1371/journal.pcbi.1002240 Most Random Gene Expression Signatures Are Significantly Associated with Breast Cancer Outcome
https://doi.org/10.1038/nature11393 Distinct contribution of stem and progenitor cells to epidermal maintenance
https://doi.org/10.1038/s42255-018-0017-4 Microbial regulation of organismal energy homeostasis
https://doi.org/10.1038/ng.1004 Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome
https://doi.org/10.1016/j.bpg.2013.03.007 Diabetes, obesity and gut microbiota
https://doi.org/10.1172/jci85664 Lung-resident eosinophils represent a distinct regulatory eosinophil subset
https://doi.org/10.1016/j.cell.2018.09.004 Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer
https://doi.org/10.1136/gutjnl-2016-312729 Gut microbiome and liver diseases
https://doi.org/10.1017/s0007114516004037 Can probiotics modulate human disease by impacting intestinal barrier function?
https://doi.org/10.1038/nm.4135 p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity
https://doi.org/10.1038/s41586-020-03046-1 Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis
https://doi.org/10.1016/j.cell.2018.03.067 Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation
https://doi.org/10.1016/j.copbio.2015.09.001 Prebiotics: why definitions matter
https://doi.org/10.1038/s41575-018-0025-6 Gut microbiota-mediated inflammation in obesity: a link with gastrointestinal cancer
https://doi.org/10.1016/j.chom.2013.09.012 Microbial Modulation of Energy Availability in the Colon Regulates Intestinal Transit
https://doi.org/10.1038/ncomms14684 Defining stem cell dynamics and migration during wound healing in mouse skin epidermis
https://doi.org/10.1084/jem.20201012 Neutrophil extracellular traps infiltrate the lung airway, interstitial, and vascular compartments in severe COVID-19
https://doi.org/10.1016/j.coph.2013.09.008 Gut microbiota, enteroendocrine functions and metabolism
https://doi.org/10.1172/jci71614 Genetics of lymphatic anomalies
https://doi.org/10.1038/nature14665 Reactivation of multipotency by oncogenic PIK3CA induces breast tumour heterogeneity
https://doi.org/10.1136/gutjnl-2017-314508 Akkermansia muciniphila induces gut microbiota remodelling and controls islet autoimmunity in NOD mice
https://doi.org/10.1038/nrendo.2015.211 Endocannabinoids — at the crossroads between the gut microbiota and host metabolism
https://doi.org/10.1172/jci.insight.91487 CXCL13-producing TFH cells link immune suppression and adaptive memory in human breast cancer
https://doi.org/10.1038/ncb3024 Early lineage restriction in temporally distinct populations of Mesp1 progenitors during mammalian heart development
https://doi.org/10.1016/j.it.2017.05.006 Integrating Next-Generation Dendritic Cell Vaccines into the Current Cancer Immunotherapy Landscape
https://doi.org/10.1038/s41467-019-11843-0 Non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung
https://doi.org/10.1038/s41590-019-0493-z House dust mites activate nociceptor–mast cell clusters to drive type 2 skin inflammation
https://doi.org/10.1016/j.molmet.2016.05.011 How gut microbes talk to organs: The role of endocrine and nervous routes
https://doi.org/10.1038/nm.4332 Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation
https://doi.org/10.1126/science.aao4174 Defining the earliest step of cardiovascular lineage segregation by single-cell RNA-seq
https://doi.org/10.1038/s43018-023-00595-y Cancer cell plasticity during tumor progression, metastasis and response to therapy
https://doi.org/10.1128/mbio.01011-14 Saccharomyces boulardii Administration Changes Gut Microbiota and Reduces Hepatic Steatosis, Low - Grade Inflammation, and Fat Mass in Obese and Type 2 Diabetic db / db Mice
https://doi.org/10.1210/er.2018-00280 The Gut Microbiome Influences Host Endocrine Functions
https://doi.org/10.1038/s41579-019-0314-2 Mechanomicrobiology: how bacteria sense and respond to forces
https://doi.org/10.1038/nchembio.1141 Metabolite damage and its repair or pre-emption
https://doi.org/10.1016/j.devcel.2015.06.016 Modulation of Ciliary Phosphoinositide Content Regulates Trafficking and Sonic Hedgehog Signaling Output
https://doi.org/10.3920/bm2012.0065 Gut microbiota controls adipose tissue expansion, gut barrier and glucose metabolism: novel insights into molecular targets and interventions using prebiotics
https://doi.org/10.1007/s00125-015-3712-7 Gut microorganisms as promising targets for the management of type 2 diabetes
https://doi.org/10.1038/s41574-022-00794-0 The gut microbiota in obesity and weight management: microbes as friends or foe?
https://doi.org/10.1183/13993003.01824-2014 Asthma phenotypes and IgE responses
https://doi.org/10.1038/s41586-018-0243-7 Codon-specific translation reprogramming promotes resistance to targeted therapy
https://doi.org/10.1080/19490976.2020.1737307 Pasteurized Akkermansia muciniphila increases whole-body energy expenditure and fecal energy excretion in diet-induced obese mice
https://doi.org/10.1126/science.aat1178 A molecular mechanism for Wnt ligand-specific signaling
https://doi.org/10.1136/gutjnl-2024-333378 What defines a healthy gut microbiome?
https://doi.org/10.1016/j.celrep.2015.09.032 Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome
https://doi.org/10.1016/j.neuron.2017.02.001 Hallmarks of Alzheimer’s Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain
https://doi.org/10.1038/s41467-018-04365-8 IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
https://doi.org/10.1158/0008-5472.can-12-1377 Neogenesis of Lymphoid Structures and Antibody Responses Occur in Human Melanoma Metastases
https://doi.org/10.1016/j.molmet.2016.10.011 Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satiety
https://doi.org/10.1007/s11154-014-9288-6 Gut microbiota and GLP-1
https://doi.org/10.1136/gutjnl-2019-319726 Discovery of the gut microbial signature driving the efficacy of prebiotic intervention in obese patients
https://doi.org/10.1016/j.immuni.2017.02.016 Exposure to Bacterial CpG DNA Protects from Airway Allergic Inflammation by Expanding Regulatory Lung Interstitial Macrophages
https://doi.org/10.1038/ncomms6648 Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status
https://doi.org/10.1186/s40168-021-01097-8 Novel insights into the genetically obese (ob/ob) and diabetic (db/db) mice: two sides of the same coin
https://doi.org/10.1038/ncomms11828 Circadian regulation of human cortical excitability
https://doi.org/10.3389/fimmu.2015.00034 Tryptophan-Degrading Enzymes in Tumoral Immune Resistance
https://doi.org/10.1038/ncb2600 Multipotent and unipotent progenitors contribute to prostate postnatal development
https://doi.org/10.1016/j.devcel.2015.11.005 A Dynamic Unfolded Protein Response Contributes to the Control of Cortical Neurogenesis
https://doi.org/10.1161/circresaha.121.318142 Lymphatic Malformations: Genetics, Mechanisms and Therapeutic Strategies
https://doi.org/10.1038/s41467-017-00784-1 Resistance to cancer immunotherapy mediated by apoptosis of tumor-infiltrating lymphocytes
https://doi.org/10.1016/j.molmed.2015.04.001 EGFR and NF-κB: partners in cancer
https://doi.org/10.1038/s41574-018-0143-9 Microbiota and metabolites in metabolic diseases
https://doi.org/10.1161/circresaha.121.318145 Genetic Basis and Therapies for Vascular Anomalies
https://doi.org/10.1136/gutjnl-2020-321173 Bacteria-derived long chain fatty acid exhibits anti-inflammatory properties in colitis
https://doi.org/10.1155/2015/948501 Human Tumor Antigens and Cancer Immunotherapy
https://doi.org/10.1080/19490976.2020.1849998 From correlation to causality: the case of Subdoligranulum
https://doi.org/10.1136/gutjnl-2020-323778 Dysosmobacter welbionis is a newly isolated human commensal bacterium preventing diet-induced obesity and metabolic disorders in mice
https://doi.org/10.1038/onc.2011.184 Cancer cells in epithelial-to-mesenchymal transition and tumor-propagating–cancer stem cells: distinct, overlapping or same populations