Publications in OpenAlex of which a co-author is affiliated to this organization
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| Title | DOI |
|---|---|
| https://doi.org/10.1056/nejmoa1607948 | Romosozumab Treatment in Postmenopausal Women with Osteoporosis |
| https://doi.org/10.1073/pnas.0308208101 | The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam |
| https://doi.org/10.1056/nejmoa1708322 | Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis |
| https://doi.org/10.1183/09031936.04.00013904 | Prevalence and rate of diagnosis of allergic rhinitis in Europe |
| https://doi.org/10.1007/s10565-011-9208-4 | Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins |
| https://doi.org/10.1038/nrd4126 | New avenues for anti-epileptic drug discovery and development |
| https://doi.org/10.1016/j.chembiol.2012.12.006 | Developing Irreversible Inhibitors of the Protein Kinase Cysteinome |
| https://doi.org/10.1016/j.biopsych.2020.02.001 | The β-Secretase BACE1 in Alzheimer’s Disease |
| https://doi.org/10.1038/nature07390 | Direct evidence of extensive diversity of HIV-1 in Kinshasa by 1960 |
| https://doi.org/10.1126/scitranslmed.aaf6667 | Imaging synaptic density in the living human brain |
| https://doi.org/10.1111/epi.14596 | The epidemiology of drug‐resistant epilepsy: A systematic review and meta‐analysis |
| https://doi.org/10.1016/j.jpba.2007.06.013 | Harmonization of strategies for the validation of quantitative analytical procedures |
| https://doi.org/10.1016/s0014-2999(98)00410-5 | Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy |
| https://doi.org/10.1136/ard.2008.101659 | Efficacy and safety of certolizumab pegol plus methotrexate in active rheumatoid arthritis: the RAPID 2 study. A randomised controlled trial |
| https://doi.org/10.1136/annrheumdis-2013-204231 | Efficacy of certolizumab pegol on signs and symptoms of axial spondyloarthritis including ankylosing spondylitis: 24-week results of a double-blind randomised placebo-controlled Phase 3 study |
| https://doi.org/10.1002/mds.21475 | Levodopa‐induced dyskinesias |
| https://doi.org/10.1016/s0140-6736(17)31613-6 | Romosozumab (sclerostin monoclonal antibody) versus teriparatide in postmenopausal women with osteoporosis transitioning from oral bisphosphonate therapy: a randomised, open-label, phase 3 trial |
| https://doi.org/10.1136/annrheumdis-2013-203696 | Effect of certolizumab pegol on signs and symptoms in patients with psoriatic arthritis: 24-week results of a Phase 3 double-blind randomised placebo-controlled study (RAPID-PsA) |
| https://doi.org/10.1111/j.1528-1157.2000.tb00323.x | Multicenter Double‐Blind, Randomized, Placebo‐Controlled Trial of Levetiracetam as Add‐On Therapy in Patients with Refractory Partial Seizures |
| https://doi.org/10.3389/fphar.2020.00356 | Modeling Parkinson’s Disease With the Alpha-Synuclein Protein |
| https://doi.org/10.1111/j.1528-1157.2000.tb04605.x | Efficacy and Tolerability of Levetiracetam 3000 mg/d in Patients with Refractory Partial Seizures: A Multicenter, Double‐Blind, Responder‐Selected Study Evaluating Monotherapy |
| https://doi.org/10.1038/s41573-023-00688-4 | Applications of single-cell RNA sequencing in drug discovery and development |
| https://doi.org/10.1136/annrheumdis-2017-212196 | Lack of placental transfer of certolizumab pegol during pregnancy: results from CRIB, a prospective, postmarketing, pharmacokinetic study |
| https://doi.org/10.1056/nejmoa2102383 | Bimekizumab versus Secukinumab in Plaque Psoriasis |
| https://doi.org/10.1002/anie.201404436 | A General Copper‐Mediated Nucleophilic 18F Fluorination of Arenes |
| https://doi.org/10.1038/nm.3384 | Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression |
| https://doi.org/10.1038/s41557-019-0353-3 | Photoredox catalysis with aryl sulfonium salts enables site-selective late-stage fluorination |
| https://doi.org/10.1002/cpt.1013 | Physiologically Based Pharmacokinetic Model Qualification and Reporting Procedures for Regulatory Submissions: A Consortium Perspective |
| https://doi.org/10.1073/pnas.1511003112 | Imaging robust microglial activation after lipopolysaccharide administration in humans with PET |
| https://doi.org/10.1016/j.ijpharm.2005.05.014 | Preparation and characterization of nanocrystals for solubility and dissolution rate enhancement of nifedipine |
| https://doi.org/10.1136/ard.2008.099291 | Efficacy and safety of certolizumab pegol monotherapy every 4 weeks in patients with rheumatoid arthritis failing previous disease-modifying antirheumatic therapy: the FAST4WARD study |
| https://doi.org/10.1038/sj.bjp.0704766 | The anti‐epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA‐ and glycine‐gated currents |
| https://doi.org/10.1038/s41586-020-2288-7 | C9orf72 suppresses systemic and neural inflammation induced by gut bacteria |
| https://doi.org/10.1016/j.jpba.2007.06.032 | Harmonization of strategies for the validation of quantitative analytical procedures |
| https://doi.org/10.2967/jnumed.115.168179 | Synthesis and Preclinical Evaluation of11C-UCB-J as a PET Tracer for Imaging the Synaptic Vesicle Glycoprotein 2A in the Brain |
| https://doi.org/10.1210/jc.2017-02163 | A Phase III Randomized Placebo-Controlled Trial to Evaluate Efficacy and Safety of Romosozumab in Men With Osteoporosis |
| https://doi.org/10.1038/aps.2016.125 | Advances in the study of berberine and its derivatives: a focus on anti-inflammatory and anti-tumor effects in the digestive system |
| https://doi.org/10.1016/j.ejps.2020.105280 | Impact of gastrointestinal physiology on drug absorption in special populations––An UNGAP review |
| https://doi.org/10.1016/s0140-6736(21)00125-2 | Bimekizumab versus ustekinumab for the treatment of moderate to severe plaque psoriasis (BE VIVID): efficacy and safety from a 52-week, multicentre, double-blind, active comparator and placebo controlled phase 3 trial |
| https://doi.org/10.1111/epi.13965 | Commonalities in epileptogenic processes from different acute brain insults: Do they translate? |
| https://doi.org/10.1016/s0140-6736(21)00126-4 | Bimekizumab efficacy and safety in moderate to severe plaque psoriasis (BE READY): a multicentre, double-blind, placebo-controlled, randomised withdrawal phase 3 trial |
| https://doi.org/10.1002/anie.201906672 | Aryl Sulfonium Salts for Site‐Selective Late‐Stage Trifluoromethylation |
| https://doi.org/10.1212/01.wnl.0000268699.34614.d3 | Placebo-controlled study of levetiracetam in idiopathic generalized epilepsy |
| https://doi.org/10.1136/annrheumdis-2017-212127 | Dual IL-17A and IL-17F neutralisation by bimekizumab in psoriatic arthritis: evidence from preclinical experiments and a randomised placebo-controlled clinical trial that IL-17F contributes to human chronic tissue inflammation |
| https://doi.org/10.1007/s11095-007-9429-7 | In Vivo Methods for the Assessment of Topical Drug Bioavailability |
| https://doi.org/10.1016/j.ejphar.2011.04.064 | Binding characteristics of brivaracetam, a selective, high affinity SV2A ligand in rat, mouse and human brain: Relationship to anti-convulsant properties |
| https://doi.org/10.1212/01.wnl.0000297512.18364.40 | Levetiracetam for the treatment of idiopathic generalized epilepsy with myoclonic seizures |
| https://doi.org/10.1038/s41573-019-0048-x | Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models |
| https://doi.org/10.1016/j.yrtph.2018.04.014 | In silico toxicology protocols |
| https://doi.org/10.1016/j.nbd.2012.05.021 | Constitutive secretion of tau protein by an unconventional mechanism |
| https://doi.org/10.1007/s00415-019-09348-3 | Does the MDS-UPDRS provide the precision to assess progression in early Parkinson’s disease? Learnings from the Parkinson’s progression marker initiative cohort |
| https://doi.org/10.1002/art.39856 | Efficacy and Safety of Epratuzumab in Moderately to Severely Active Systemic Lupus Erythematosus: Results From Two Phase III Randomized, Double‐Blind, Placebo‐Controlled Trials |
| https://doi.org/10.1002/jbmr.3452 | Effects of 24 Months of Treatment With Romosozumab Followed by 12 Months of Denosumab or Placebo in Postmenopausal Women With Low Bone Mineral Density: A Randomized, Double-Blind, Phase 2, Parallel Group Study |
| https://doi.org/10.1056/nejmoa2102388 | Bimekizumab versus Adalimumab in Plaque Psoriasis |
| https://doi.org/10.1016/s1474-4422(23)00080-7 | Safety and efficacy of zilucoplan in patients with generalised myasthenia gravis (RAISE): a randomised, double-blind, placebo-controlled, phase 3 study |
| https://doi.org/10.1021/jm030913e | Discovery of 4-Substituted Pyrrolidone Butanamides as New Agents with Significant Antiepileptic Activity |
| https://doi.org/10.1093/brain/awab162 | Early childhood epilepsies: epidemiology, classification, aetiology, and socio-economic determinants |
| https://doi.org/10.1038/s41573-022-00633-x | The evolving role of investigative toxicology in the pharmaceutical industry |
| https://doi.org/10.1038/bjp.2008.198 | Anti‐convulsive and anti‐epileptic properties of brivaracetam (ucb 34714), a high‐affinity ligand for the synaptic vesicle protein, SV2A |
| https://doi.org/10.1177/0271678x17724947 | Kinetic evaluation and test–retest reproducibility of [11C]UCB-J, a novel radioligand for positron emission tomography imaging of synaptic vesicle glycoprotein 2A in humans |
| https://doi.org/10.1111/epi.13200 | Diagnostic methods and treatment options for focal cortical dysplasia |
| https://doi.org/10.1038/nature19827 | 1970s and ‘Patient 0’ HIV-1 genomes illuminate early HIV/AIDS history in North America |
| https://doi.org/10.1212/wnl.0b013e3181a82687 | Electroencephalographic monitoring during hypothermia after pediatric cardiac arrest |
| https://doi.org/10.1093/brain/awaa325 | Pathophysiological subtypes of Alzheimer’s disease based on cerebrospinal fluid proteomics |
| https://doi.org/10.1002/wsbm.1489 | Molecular networks in Network Medicine: Development and applications |
| https://doi.org/10.1111/j.1365-2222.2007.02861.x | Confirmation of the association between high levels of immunoglobulin E food sensitization and eczema in infancy: an international study |
| https://doi.org/10.1016/s1359-6446(05)03625-1 | Keynote review: Histamine H3 receptor antagonists reach out for the clinic |
| https://doi.org/10.1038/s41467-020-18723-y | Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders |
| https://doi.org/10.1021/jacs.7b03131 | Derisking the Cu-Mediated 18F-Fluorination of Heterocyclic Positron Emission Tomography Radioligands |
| https://doi.org/10.1136/bmj.m4856 | STaRT-RWE: structured template for planning and reporting on the implementation of real world evidence studies |
| https://doi.org/10.1016/j.eplepsyres.2014.11.021 | Current understanding of the mechanism of action of the antiepileptic drug lacosamide |
| https://doi.org/10.1016/j.coi.2009.05.018 | Yellow fever vaccine — how does it work and why do rare cases of serious adverse events take place? |
| https://doi.org/10.1177/2168479015580384 | Partnering With Patients in the Development and Lifecycle of Medicines: A Call for Action |
| https://doi.org/10.2165/11587550-000000000-00000 | A Pooled Analysis of Lacosamide Clinical Trial Data Grouped by Mechanism of Action of Concomitant Antiepileptic Drugs |
| https://doi.org/10.1126/scitranslmed.aan1208 | The FcRn inhibitor rozanolixizumab reduces human serum IgG concentration: A randomized phase 1 study |
| https://doi.org/10.1021/jacs.0c03881 | Organophotoredox Hydrodefluorination of Trifluoromethylarenes with Translational Applicability to Drug Discovery |
| https://doi.org/10.1080/10837450902891295 | Drug metabolism and pharmacokinetics |
| https://doi.org/10.1016/j.taap.2013.09.003 | Preclinical safety profile of trastuzumab emtansine (T-DM1): Mechanism of action of its cytotoxic component retained with improved tolerability |
| https://doi.org/10.1016/j.jaad.2018.03.037 | Dual neutralization of both interleukin 17A and interleukin 17F with bimekizumab in patients with psoriasis: Results from BE ABLE 1, a 12-week randomized, double-blinded, placebo-controlled phase 2b trial |
| https://doi.org/10.1002/jbmr.3622 | One Year of Romosozumab Followed by Two Years of Denosumab Maintains Fracture Risk Reductions: Results of the FRAME Extension Study |
| https://doi.org/10.1007/s00401-019-02087-9 | From the prion-like propagation hypothesis to therapeutic strategies of anti-tau immunotherapy |
| https://doi.org/10.1039/c3cs60309a | Nanoscale optical probes for cellular imaging |
| https://doi.org/10.1038/ncomms7031 | Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus |
| https://doi.org/10.1111/epi.13783 | Neuroinflammatory targets and treatments for epilepsy validated in experimental models |
| https://doi.org/10.1093/brain/awz100 | Prevention of tau seeding and propagation by immunotherapy with a central tau epitope antibody |
| https://doi.org/10.1177/147323001003800402 | Patient Perceptions concerning Pain Management in the Treatment of Rheumatoid Arthritis |
| https://doi.org/10.1371/journal.pone.0189161 | Feasibility of large-scale deployment of multiple wearable sensors in Parkinson's disease |
| https://doi.org/10.1002/art.40508 | Pregnancy Outcomes After Exposure to Certolizumab Pegol |
| https://doi.org/10.1093/jn/132.5.967 | Dietary Fructans, but Not Cellulose, Decrease Triglyceride Accumulation in the Liver of Obese Zucker fa/fa Rats |
| https://doi.org/10.1016/s0140-6736(16)31651-8 | Head-to-head comparison of certolizumab pegol versus adalimumab in rheumatoid arthritis: 2-year efficacy and safety results from the randomised EXXELERATE study |
| https://doi.org/10.3390/s17102338 | Automated Epileptic Seizure Detection Based on Wearable ECG and PPG in a Hospital Environment |
| https://doi.org/10.1046/j.1472-8206.2003.00140.x | Drug metabolism and disposition in children |
| https://doi.org/10.1136/annrheumdis-2017-211384 | Minimal to no transfer of certolizumab pegol into breast milk: results from CRADLE, a prospective, postmarketing, multicentre, pharmacokinetic study |
| https://doi.org/10.1007/s40263-016-0384-x | Synaptic Vesicle Glycoprotein 2A Ligands in the Treatment of Epilepsy and Beyond |
| https://doi.org/10.1002/cmdc.201300525 | Binding Mode and Structure–Activity Relationships around Direct Inhibitors of the Nrf2–Keap1 Complex |
| https://doi.org/10.1038/nature25749 | Palladium-catalysed electrophilic aromatic C–H fluorination |
| https://doi.org/10.1016/j.cgh.2011.04.031 | Certolizumab Pegol for Active Crohn's Disease: A Placebo-Controlled, Randomized Trial |
| https://doi.org/10.1016/j.neuropharm.2007.11.021 | SV2A protein is a broad-spectrum anticonvulsant target: Functional correlation between protein binding and seizure protection in models of both partial and generalized epilepsy |
| https://doi.org/10.1136/gutjnl-2012-302262 | Endoscopic improvement of mucosal lesions in patients with moderate to severe ileocolonic Crohn's disease following treatment with certolizumab pegol |
| https://doi.org/10.1016/j.coph.2014.01.001 | Schizophrenia: from dopaminergic to glutamatergic interventions |