Vlaams Instituut voor Biotechnologie

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Title DOI
https://doi.org/10.1038/nprot.2013.084 De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis
https://doi.org/10.1038/35025220 Angiogenesis in cancer and other diseases
https://doi.org/10.1093/nar/30.1.325 PlantCARE, a database of plant cis-acting regulatory elements and a portal to tools for in silico analysis of promoter sequences
https://doi.org/10.1146/annurev.arplant.54.031902.134938 Lignin Biosynthesis
https://doi.org/10.1038/nm0603-653 Angiogenesis in health and disease
https://doi.org/10.1038/74651 Mechanisms of angiogenesis and arteriogenesis
https://doi.org/10.1038/380435a0 Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
https://doi.org/10.1016/s1360-1385(02)02251-3 GATEWAY™ vectors for Agrobacterium-mediated plant transformation
https://doi.org/10.1038/nature04478 Angiogenesis in life, disease and medicine
https://doi.org/10.1038/cdd.2008.150 Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
https://doi.org/10.1038/nature10361 Crystal structure of the β2 adrenergic receptor–Gs protein complex
https://doi.org/10.1016/j.ccr.2005.03.023 Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
https://doi.org/10.1093/nar/gki387 The FoldX web server: an online force field
https://doi.org/10.1038/28867 Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
https://doi.org/10.1038/s41422-019-0164-5 The molecular machinery of regulated cell death
https://doi.org/10.1038/cdd.2011.96 Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
https://doi.org/10.1146/annurev.arplant.57.032905.105441 SUGAR SENSING AND SIGNALING IN PLANTS: Conserved and Novel Mechanisms
https://doi.org/10.1038/nrd3505 The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics
https://doi.org/10.1038/ng.654 The genome of the domesticated apple (Malus × domestica Borkh.)
https://doi.org/10.1038/19083 A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain
https://doi.org/10.1038/ng.803 Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
https://doi.org/10.1007/s000180050041 Dual action of the active oxygen species during plant stress responses
https://doi.org/10.1182/blood-2013-08-518886 Clinical and biological implications of driver mutations in myelodysplastic syndromes
https://doi.org/10.1038/34910 Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein
https://doi.org/10.1016/j.neuron.2022.10.020 Microglia states and nomenclature: A field at its crossroads
https://doi.org/10.1038/nature09648 Structure of a nanobody-stabilized active state of the β2 adrenoceptor
https://doi.org/10.1038/87904 Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions
https://doi.org/10.1016/j.cell.2006.06.025 OPA1 Controls Apoptotic Cristae Remodeling Independently from Mitochondrial Fusion
https://doi.org/10.1023/b:phyt.0000047809.65444.a4 Lignins: Natural polymers from oxidative coupling of 4-hydroxyphenyl- propanoids
https://doi.org/10.1038/nature05017 Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21
https://doi.org/10.1002/(sici)1097-0010(20000515)80:7<825::aid-jsfa598>3.0.co;2-6 PlantL-ascorbic acid: chemistry, function, metabolism, bioavailability and effects of processing
https://doi.org/10.1016/s0140-6736(05)67861-0 Autologous bone marrow-derived stem-cell transfer in patients with ST-segment elevation myocardial infarction: double-blind, randomised controlled trial
https://doi.org/10.1038/s41586-020-2188-x A reference map of the human binary protein interactome
https://doi.org/10.1016/s0092-8674(00)81010-7 Targeted Deficiency or Cytosolic Truncation of the VE-cadherin Gene in Mice Impairs VEGF-Mediated Endothelial Survival and Angiogenesis
https://doi.org/10.1086/320609 De Novo Mutations in the Sodium-Channel Gene SCN1A Cause Severe Myoclonic Epilepsy of Infancy
https://doi.org/10.1093/emboj/16.16.4806 Catalase is a sink for H2O2 and is indispensable for stress defence in C3 plants
https://doi.org/10.1038/nm.2425 Foxp3+ follicular regulatory T cells control the germinal center response
https://doi.org/10.1038/nrm977 uPAR: a versatile signalling orchestrator
https://doi.org/10.1038/nbt1282 Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88
https://doi.org/10.1002/bies.20493 Reactive oxygen species as signals that modulate plant stress responses and programmed cell death
https://doi.org/10.1038/ng0797-303 Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene
https://doi.org/10.1038/nrg2600 The evolutionary significance of ancient genome duplications
https://doi.org/10.1073/pnas.1415518111 Synchronized renal tubular cell death involves ferroptosis
https://doi.org/10.1002/bies.20293 From 2R to 3R: evidence for a fish‐specific genome duplication (FSGD)
https://doi.org/10.1038/nrmicro.2017.58 The resilience of the intestinal microbiota influences health and disease
https://doi.org/10.1126/science.abf4588 Neuropixels 2.0: A miniaturized high-density probe for stable, long-term brain recordings
https://doi.org/10.1038/nature06556 The genome of Laccaria bicolor provides insights into mycorrhizal symbiosis
https://doi.org/10.1038/nm731 Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1
https://doi.org/10.1016/j.devcel.2010.05.008 Nitrate-Regulated Auxin Transport by NRT1.1 Defines a Mechanism for Nutrient Sensing in Plants
https://doi.org/10.1016/s0008-6363(00)00281-9 Molecular mechanisms of blood vessel growth
https://doi.org/10.1038/88842 Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
https://doi.org/10.1038/nature08854 NINJA connects the co-repressor TOPLESS to jasmonate signalling
https://doi.org/10.1105/tpc.19.00335 Brassinosteroids: Multidimensional Regulators of Plant Growth, Development, and Stress Responses
https://doi.org/10.1146/annurev.genet.38.072902.092831 Duplication and Divergence: The Evolution of New Genes and Old Ideas
https://doi.org/10.1083/jcb.200307137 Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands
https://doi.org/10.1038/ng.343 Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates
https://doi.org/10.1073/pnas.0501102102 Modeling gene and genome duplications in eukaryotes
https://doi.org/10.1016/s0896-6273(03)00205-8 Aph-1, Pen-2, and Nicastrin with Presenilin Generate an Active γ-Secretase Complex
https://doi.org/10.1073/pnas.1722335115 MYB72-dependent coumarin exudation shapes root microbiome assembly to promote plant health
https://doi.org/10.1093/jxb/erq282 Catalase function in plants: a focus on Arabidopsis mutants as stress-mimic models
https://doi.org/10.1084/jem.187.9.1477 Inhibition of Caspases Increases the Sensitivity of L929 Cells to Necrosis Mediated by Tumor Necrosis Factor
https://doi.org/10.1038/nmeth.1280 An empirical framework for binary interactome mapping
https://doi.org/10.1038/nbt1203 Gene prioritization through genomic data fusion
https://doi.org/10.1146/annurev.genet.40.110405.090431 Cell Cycle Regulation in Plant Development
https://doi.org/10.1073/pnas.0604795103 Genome analysis of the smallest free-living eukaryote Ostreococcus tauri unveils many unique features
https://doi.org/10.1038/sj.onc.1203249 More than one way to die: apoptosis, necrosis and reactive oxygen damage
https://doi.org/10.1038/ng1211 VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death
https://doi.org/10.1104/pp.103.026484 Genome-Wide Characterization of the Lignification Toolbox in Arabidopsis  
https://doi.org/10.1038/35140 Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis thaliana
https://doi.org/10.1038/sj.cdd.4401724 Classification of cell death: recommendations of the Nomenclature Committee on Cell Death
https://doi.org/10.1105/tpc.107.052126 Ethylene Regulates Root Growth through Effects on Auxin Biosynthesis and Transport-Dependent Auxin Distribution
https://doi.org/10.1056/nejmoa0805384 Recurrent Rearrangements of Chromosome 1q21.1 and Variable Pediatric Phenotypes
https://doi.org/10.1016/j.cell.2009.01.020 Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization
https://doi.org/10.1038/13459 Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure
https://doi.org/10.1038/nri2815 The X chromosome in immune functions: when a chromosome makes the difference
https://doi.org/10.1038/nprot.2014.039 A general protocol for the generation of Nanobodies for structural biology
https://doi.org/10.1016/j.tplants.2009.05.002 Arabidopsis lateral root development: an emerging story
https://doi.org/10.1038/nmeth1109-786 Improved visualization of protein consensus sequences by iceLogo
https://doi.org/10.1073/pnas.0308114100 A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis
https://doi.org/10.1182/blood-2012-04-416594 The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways
https://doi.org/10.1038/s41571-019-0203-7 Navigating metabolic pathways to enhance antitumour immunity and immunotherapy
https://doi.org/10.1038/nm884 Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1
https://doi.org/10.1016/j.cgh.2006.03.028 A Phase I Trial With Transgenic Bacteria Expressing Interleukin-10 in Crohn’s Disease
https://doi.org/10.1016/s0014-5793(97)01062-4 Selection and identification of single domain antibody fragments from camel heavy‐chain antibodies
https://doi.org/10.1038/nbt1329 The minimum information about a proteomics experiment (MIAPE)
https://doi.org/10.1093/jexbot/53.372.1227 Signal transduction during oxidative stress
https://doi.org/10.1038/13484 A universal influenza A vaccine based on the extracellular domain of the M2 protein
https://doi.org/10.1016/j.tim.2011.01.001 Cecal ligation and puncture: the gold standard model for polymicrobial sepsis?
https://doi.org/10.1016/j.cell.2006.06.021 Mitochondrial Rhomboid PARL Regulates Cytochrome c Release during Apoptosis via OPA1-Dependent Cristae Remodeling
https://doi.org/10.1093/nar/27.1.295 PlantCARE, a plant cis-acting regulatory element database
https://doi.org/10.1038/nm721 Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice
https://doi.org/10.1016/s0168-9452(96)04541-4 An Agrobacterium-mediated transient gene expression system for intact leaves
https://doi.org/10.1016/s1535-6108(02)00051-x Molecular mechanisms of lymphangiogenesis in health and disease
https://doi.org/10.1038/83358 The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling
https://doi.org/10.1182/blood-2002-12-3775 The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion
https://doi.org/10.1016/j.tplants.2008.12.003 How relevant are flavonoids as antioxidants in plants?
https://doi.org/10.1016/j.tplants.2007.03.012 Plant dormancy in the perennial context
https://doi.org/10.1093/nar/gkae410 The Galaxy platform for accessible, reproducible, and collaborative data analyses: 2024 update
https://doi.org/10.18637/jss.v007.i10 zt: A Software Tool for Simple and Partial Mantel Tests
https://doi.org/10.1073/pnas.94.13.7076 The AP2 domain of APETALA2 defines a large new family of DNA binding proteins in  Arabidopsis