Biomedical Informatics Research Center Antwerp

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Title DOI
https://doi.org/10.1073/pnas.0407162101 Accelerated telomere shortening in response to life stress
https://doi.org/10.1056/nejmoa1609214 Fulminant Myocarditis with Combination Immune Checkpoint Blockade
https://doi.org/10.1056/nejmoa1711584 Balanced Crystalloids versus Saline in Critically Ill Adults
https://doi.org/10.1056/nejmoa1711586 Balanced Crystalloids versus Saline in Noncritically Ill Adults
https://doi.org/10.1073/pnas.0800468105 An overlapping essential gene in the Potyviridae
https://doi.org/10.1073/pnas.1118857109 The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations
https://doi.org/10.1073/pnas.95.4.1961 Genetic traces of ancient demography
https://doi.org/10.1126/science.1673802 Linkage of a Cardiac Arrhythmia, the Long QT Syndrome, and the Harvey ras -1 Gene
https://doi.org/10.1172/jci75436 Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature
https://doi.org/10.1186/1757-4749-5-10 Differences in gut microbiota composition between obese and lean children: a cross-sectional study
Mice lacking angiotensin-converting enzyme have low blood pressure, renal pathology, and reduced male fertility.
Microsatellite instability in sporadic colon cancer is associated with an improved prognosis at the population level.
A dual-luciferase reporter system for studying recoding signals.
https://doi.org/10.1073/pnas.0702703104 Telomere length is paternally inherited and is associated with parental lifespan
Methylenetetrahydrofolate reductase, diet, and risk of colon cancer.
Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: a population-based study.
https://doi.org/10.1073/pnas.0801073105 Microsatellites as EWS/FLI response elements in Ewing's sarcoma
https://doi.org/10.1172/jci118253 A mouse model for the delta F508 allele of cystic fibrosis.
https://doi.org/10.1073/pnas.0505690102 Direct regulation of intestinal fate by Notch
https://doi.org/10.1172/jci119419 The critical role of tissue angiotensin-converting enzyme as revealed by gene targeting in mice.
https://doi.org/10.1002/mas.21551 A tutorial in small molecule identification via electrospray ionization‐mass spectrometry: The practical art of structural elucidation
https://doi.org/10.1001/archinternmed.2009.263 Timely Follow-up of Abnormal Diagnostic Imaging Test Results in an Outpatient Setting
https://doi.org/10.1001/2013.jamainternmed.61 Information Overload and Missed Test Results in Electronic Health Record–Based Settings
https://doi.org/10.1016/j.ebiom.2021.103722 Characterizing Long COVID: Deep Phenotype of a Complex Condition
https://doi.org/10.1073/pnas.0510164103 Somitic origin of limb muscle satellite and side population cells
https://doi.org/10.1056/nejmoa2208415 Oxygen-Saturation Targets for Critically Ill Adults Receiving Mechanical Ventilation
https://doi.org/10.3389/fimmu.2019.02820 Detection of Enriched T Cell Epitope Specificity in Full T Cell Receptor Sequence Repertoires
https://doi.org/10.1158/1055-9965.epi-08-0935 Obesity and Weight Gain in Adulthood and Telomere Length
https://doi.org/10.1093/gerona/56.3.b130 Familial Excess Longevity in Utah Genealogies
https://doi.org/10.1073/pnas.1006437108 Deletion of mouse Porcn blocks Wnt ligand secretion and reveals an ectodermal etiology of human focal dermal hypoplasia/Goltz syndrome
E. coli ribosomes re-phase on retroviral frameshift signals at rates ranging from 2 to 50 percent.
https://doi.org/10.1073/pnas.1009269107 Initiation context modulates autoregulation of eukaryotic translation initiation factor 1 (eIF1)
https://doi.org/10.1093/molbev/13.7.895 Mitochondrial mismatch analysis is insensitive to the mutational process
https://doi.org/10.1093/oxfordjournals.molbev.a003795 Global Patterns of Human DNA Sequence Variation in a 10-kb Region on Chromosome 1
https://doi.org/10.1016/j.ebiom.2018.10.013 The relationship between transmission time and clustering methods in Mycobacterium tuberculosis epidemiology
https://doi.org/10.18632/aging.100235 Telomere length in blood, buccal cells, and fibroblasts from patients with inherited bone marrow failure syndromes
https://doi.org/10.1002/mas.21544 Quality control in mass spectrometry‐based proteomics
https://doi.org/10.1016/j.chemosphere.2013.01.056 Mechanistic toxicity study of perfluorooctanoic acid in zebrafish suggests mitochondrial dysfunction to play a key role in PFOA toxicity
https://doi.org/10.1073/pnas.0910875107 A mouse model of osteochondromagenesis from clonal inactivation of Ext1 in chondrocytes
https://doi.org/10.1261/rna.487907 A case for “StopGo”: Reprogramming translation to augment codon meaning of GGN by promoting unconventional termination (Stop) after addition of glycine and then allowing continued translation (Go)
https://doi.org/10.1093/ntr/ntp064 Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes
https://doi.org/10.3390/metabo3020259 Getting Your Peaks in Line: A Review of Alignment Methods for NMR Spectral Data
https://doi.org/10.1213/ane.0000000000002298 A Survey Evaluating Burnout, Health Status, Depression, Reported Alcohol and Substance Use, and Social Support of Anesthesiologists
https://doi.org/10.1002/ajmg.c.31360 Phenotypic Spectrum of Simpson–Golabi–Behmel Syndrome in a Series of 42 Cases With a Mutation in GPC3 and Review of the Literature
https://doi.org/10.1073/pnas.0902508106 Bmi1 lineage tracing identifies a self-renewing pancreatic acinar cell subpopulation capable of maintaining pancreatic organ homeostasis
https://doi.org/10.3171/2018.8.focus18332 Outcome prediction of intracranial aneurysm treatment by flow diverters using machine learning
https://doi.org/10.1093/ndt/gfz091 The use of plasma donor-derived, cell-free DNA to monitor acute rejection after kidney transplantation
https://doi.org/10.1021/acs.jproteome.8b00359 Fast Open Modification Spectral Library Searching through Approximate Nearest Neighbor Indexing
https://doi.org/10.1093/jamia/ocv115 Data integration of structured and unstructured sources for assigning clinical codes to patient stays
https://doi.org/10.1056/nejmc1213481 Early Results of the Meaningful Use Program for Electronic Health Records
https://doi.org/10.1021/acs.analchem.9b04884 spectrum_utils : A Python Package for Mass Spectrometry Data Processing and Visualization
https://doi.org/10.1097/pap.0000000000000264 Explainable AI (xAI) for Anatomic Pathology
https://doi.org/10.1093/bioinformatics/bty821 On the viability of unsupervised T-cell receptor sequence clustering for epitope preference
https://doi.org/10.1371/journal.pone.0208207 Plasma donor-derived cell-free DNA kinetics after kidney transplantation using a single tube multiplex PCR assay
https://doi.org/10.1111/nph.16490 Osmotic stress inhibits leaf growth of Arabidopsis thaliana by enhancing ARF‐mediated auxin responses
https://doi.org/10.1021/acs.jproteome.9b00291 Extremely Fast and Accurate Open Modification Spectral Library Searching of High-Resolution Mass Spectra Using Feature Hashing and Graphics Processing Units
https://doi.org/10.1007/s00204-018-2286-9 In vitro assessment of hepatotoxicity by metabolomics: a review
https://doi.org/10.1074/mcp.m113.035907 qcML: An Exchange Format for Quality Control Metrics from Mass Spectrometry Experiments
https://doi.org/10.3390/ijms222212234 Ferroptosis Induction in Multiple Myeloma Cells Triggers DNA Methylation and Histone Modification Changes Associated with Cellular Senescence
https://doi.org/10.1213/ane.0000000000001827 A Predictive Model for Extended Postanesthesia Care Unit Length of Stay in Outpatient Surgeries
https://doi.org/10.1038/s41598-017-01024-8 Multidisciplinary study of the secondary immune response in grandparents re-exposed to chickenpox
Telomere length and variation in telomere biology genes in individuals with osteosarcoma.
https://doi.org/10.1136/bmjmed-2022-000309 Consistency of covid-19 trial preprints with published reports and impact for decision making: retrospective review
https://doi.org/10.1016/j.bbih.2022.100584 Kynurenine pathway abnormalities are state-specific but not diagnosis-specific in schizophrenia and bipolar disorder
https://doi.org/10.1021/acs.jcim.3c01301 Benchmarking of Small Molecule Feature Representations for hERG, Nav1.5, and Cav1.2 Cardiotoxicity Prediction
https://doi.org/10.1016/j.bbi.2024.08.013 Immune-based Machine learning Prediction of Diagnosis and Illness State in Schizophrenia and Bipolar Disorder
https://doi.org/10.1093/infdis/jiae535 Obesity Uncovers the Presence of Inflammatory Lung Macrophage Subsets With an Adipose Tissue Transcriptomic Signature in Influenza Virus Infection
https://doi.org/10.1128/mcb.2.11.1372-1387.1982 Patterns of Integration of DNA Microinjected into Cultured Mammalian Cells: Evidence for Homologous Recombination Between Injected Plasmid DNA Molecules
https://doi.org/10.1146/annurev.bi.65.070196.003521 RECODING: Dynamic Reprogramming of Translation
https://doi.org/10.2337/diabetes.48.5.1175 A genome-wide search for type 2 diabetes susceptibility genes in Utah Caucasians.
https://doi.org/10.1073/pnas.94.7.3100 Microsatellite diversity and the demographic history of modern humans
https://doi.org/10.1212/wnl.43.7.1355 Seizure characteristics in chromosome 20 benign familial neonatal convulsions
Genetic evidence on modern human origins.
https://doi.org/10.1073/pnas.96.2.541 Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9, function together to control development of the mammary gland in response to pregnancy
Genetic distances between the Utah Mormons and related populations.
https://doi.org/10.1073/pnas.90.7.3004 Potential role for a FTZ-F1 steroid receptor superfamily member in the control of Drosophila metamorphosis.
Genetic linkage analysis in familial benign (hypocalciuric) hypercalcemia: evidence for locus heterogeneity.
https://doi.org/10.1212/wnl.44.8.1500 Sodium channel mutations in acetazolamide‐responsive myotonia congenita, paramyotonia congenita, and hyperkalemic periodic paralysis
https://doi.org/10.1152/ajpendo.00231.2003 Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion
https://doi.org/10.1073/pnas.94.21.11451 Cleft palate in mice with a targeted mutation in the γ-aminobutyric acid-producing enzyme glutamic acid decarboxylase 67
https://doi.org/10.1161/01.hyp.18.3_suppl.i29 Are there interactions and relations between genetic and environmental factors predisposing to high blood pressure?
Implementation pearls from a new guidebook on improving medication use and outcomes with clinical decision support. Effective CDS is essential for addressing healthcare performance improvement imperatives.
https://doi.org/10.1089/tmj.2006.12.24 Applying Heuristic Evaluation to Improve the Usability of a Telemedicine System
https://doi.org/10.1073/pnas.0402647101 A balance between the diap1 death inhibitor and reaper and hid death inducers controls steroid-triggered cell death in Drosophila
https://doi.org/10.1093/gerona/63.8.809 Association of Longer Telomeres With Better Health in Centenarians
https://doi.org/10.1021/jp9639861 Solvent Dependence of the First Molecular Hyperpolarizability of p-Nitroaniline Revisited
https://doi.org/10.1261/rna.5122604 P-site tRNA is a crucial initiator of ribosomal frameshifting
https://doi.org/10.1186/1471-2180-11-68 Denaturing gradient gel electrophoresis of neonatal intestinal microbiota in relation to the development of asthma
https://doi.org/10.1073/pnas.97.4.1683 Nonlinearity in genetic decoding: Homologous DNA replicase genes use alternatives of transcriptional slippage or translational frameshifting
https://doi.org/10.1353/hub.2005.0030 Balinese Y-Chromosome Perspective on the Peopling of Indonesia: Genetic Contributions from Pre-Neolithic Hunter-Gatherers, Austronesian Farmers, and Indian Traders
https://doi.org/10.1161/circgenetics.111.961797 Exome Analysis of a Family With Pleiotropic Congenital Heart Disease
https://doi.org/10.1186/1471-2105-12-405 An integrated workflow for robust alignment and simplified quantitative analysis of NMR spectrometry data
https://doi.org/10.1016/j.survophthal.2005.04.004 Computer and World Wide Web Accessibility by Visually Disabled Patients: Problems and Solutions
https://doi.org/10.1073/pnas.1102932108 Ribosomal frameshifting into an overlapping gene in the 2B-encoding region of the cardiovirus genome
https://doi.org/10.1073/pnas.1633548100 An interacting network of T-box genes directs gene expression and fate in the zebrafish mesoderm
https://doi.org/10.1063/1.471669 Determination of first hyperpolarizability of nonlinear optical chromophores by second harmonic scattering using an external reference
https://doi.org/10.4161/cc.8.12.8744 Notch and Kras in pancreatic cancer: At the crossroads of mutation, differentiation and signaling
https://doi.org/10.1542/peds.2007-3735 HLA-A33 Is Associated With Susceptibility to Enterovirus 71 Infection
https://doi.org/10.1093/hmg/ddi218 Interindividual variability and parent of origin DNA methylation differences at specific human Alu elements
https://doi.org/10.1159/000101761 Community Engagement and Informed Consent in the International HapMap Project