Innovative Medicines Initiative

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Title DOI
https://doi.org/10.1186/1471-2105-8-s3-s2 Advancing translational research with the Semantic Web
https://doi.org/10.1177/2168479015580384 Partnering With Patients in the Development and Lifecycle of Medicines: A Call for Action
https://doi.org/10.1007/s10994-008-5093-3 Finding anomalous periodic time series
https://doi.org/10.5966/sctm.2014-0110 Concise Review: Workshop Review: Understanding and Assessing the Risks of Stem Cell-Based Therapies
https://doi.org/10.1097/bor.0000000000000567 Molecular taxonomy of osteoarthritis for patient stratification, disease management and drug development: biochemical markers associated with emerging clinical phenotypes and molecular endotypes
https://doi.org/10.1038/clpt.2011.321 The Innovative Medicines Initiative: A European Response to the Innovation Challenge
https://doi.org/10.1377/hlthaff.2012.0107 Secondary Patenting Of Branded Pharmaceuticals: A Case Study Of How Patents On Two HIV Drugs Could Be Extended For Decades
https://doi.org/10.1088/0004-637x/712/2/1137 THE MASS-SIZE RELATION FROM CLOUDS TO CORES. I. A NEW PROBE OF STRUCTURE IN MOLECULAR CLOUDS
https://doi.org/10.1016/j.lanepe.2021.100289 Doubt at the core: Unspoken vaccine hesitancy among healthcare workers
https://doi.org/10.1177/2168479016659104 Culture and Process Change as a Priority for Patient Engagement in Medicines Development
https://doi.org/10.3389/fmed.2018.00231 EUPATI Guidance for Patient Involvement in Medicines Research and Development: Health Technology Assessment
https://doi.org/10.1016/j.jval.2019.01.003 R You Still Using Excel? The Advantages of Modern Software Tools for Health Technology Assessment
https://doi.org/10.1039/c7sc05448c Pentacyclic adenine: a versatile and exceptionally bright fluorescent DNA base analogue
https://doi.org/10.1007/s40273-019-00827-z Developing Open-Source Models for the US Health System: Practical Experiences and Challenges to Date with the Open-Source Value Project
https://doi.org/10.1136/rmdopen-2022-002442 Machine learning predicts response to TNF inhibitors in rheumatoid arthritis: results on the ESPOIR and ABIRISK cohorts
https://doi.org/10.1002/alz.14098 Blood DNA methylomic signatures associated with CSF biomarkers of Alzheimer's disease in the EMIF‐AD study
https://doi.org/10.1080/10837450.2024.2342953 Ten years of the manufacturing classification system: a review of literature applications and an extension of the framework to continuous manufacture
https://doi.org/10.1038/s41375-018-0045-9 The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma
https://doi.org/10.1006/iilr.2001.0175 Empowerment and Governance through Information and Communication Technologies: Women's Perspective
https://doi.org/10.1525/cmr.2015.57.3.126 Strategic Responses to Hybrid Social Ventures
https://doi.org/10.1186/1471-244x-10-91 The cross-sectional GRAS sample: A comprehensive phenotypical data collection of schizophrenic patients
https://doi.org/10.1038/nrd4520 The Innovative Medicines Initiative: an engine for regulatory science
https://doi.org/10.2165/11584920-000000000-00000 The Cost Utility of Autologous Chondrocytes Implantation Using ChondroCelect® in Symptomatic Knee Cartilage Lesions in Belgium
https://doi.org/10.1111/hex.12797 What do stakeholders expect from patient engagement: Are these expectations being met?
https://doi.org/10.1016/j.rehab.2016.03.005 Altered joint tribology in osteoarthritis: Reduced lubricin synthesis due to the inflammatory process. New horizons for therapeutic approaches
https://doi.org/10.1302/0301-620x.98b7.37274 No difference in clinical outcome between patient-matched positioning guides and conventional instrumented total knee arthroplasty two years post-operatively
https://doi.org/10.3389/fmed.2019.00275 The Innovative Medicines Initiative −10 Years of Public-Private Collaboration
https://doi.org/10.1186/2001-1326-2-2 Public‐private partnerships as driving forces in the quest for innovative medicines
https://doi.org/10.1111/ajt.12067 Cyclosporine A Drives a Th17- and Th2-Mediated Posttransplant Obliterative Airway Disease
https://doi.org/10.1016/s0140-6736(16)31425-8 Increased momentum in antimicrobial resistance research
https://doi.org/10.1007/s40273-021-01036-3 Putting Stakeholder Engagement at the Center of Health Economic Modeling for Health Technology Assessment in the United States
https://doi.org/10.1038/nrd3434 Reflections on the Innovative Medicines Initiative
https://doi.org/10.7150/thno.48110 Impact of hydroxytyrosol on stroke: tracking therapy response on neuroinflammation and cerebrovascular parameters using PET-MR imaging and on functional outcomes
https://doi.org/10.5936/csbj.201303017 THE INNOVATIVE MEDICINES INITIATIVE: A PUBLIC PRIVATE PARTNERSHIP MODEL TO FOSTER DRUG DISCOVERY
https://doi.org/10.1039/c9ta01771b Grain boundaries modified uniformly-conjoint metal/oxides via binder strategy as efficient bifunctional electrocatalysts
https://doi.org/10.1007/978-3-642-04174-7_32 Kernels for Periodic Time Series Arising in Astronomy
https://doi.org/10.1016/j.tox.2015.06.009 Importance of investigating epigenetic alterations for industry and regulators: An appraisal of current efforts by the Health and Environmental Sciences Institute
https://doi.org/10.2196/25743 Methods to Generate Innovative Research Ideas and Improve Patient and Public Involvement in Modern Epidemiological Research: Review, Patient Viewpoint, and Guidelines for Implementation of a Digital Cohort Study
https://doi.org/10.3389/fphys.2020.00584 Imaging Biomarkers and Pathobiological Profiling in a Rat Model of Drug-Induced Interstitial Lung Disease Induced by Bleomycin
https://doi.org/10.1111/epi.12300 Proposal for a “phase II” multicenter trial model for preclinical new antiepilepsy therapy development
https://doi.org/10.1080/14737159.2019.1646641 Coll2-1 and Coll2-1NO2 as exemplars of collagen extracellular matrix turnover – biomarkers to facilitate the treatment of osteoarthritis?
https://doi.org/10.1039/c9bm00667b Amphiphilic tri- and tetra-block co-polymers combining versatile functionality with facile assembly into cytocompatible nanoparticles
https://doi.org/10.1007/164_2019_293 Research Collaborations and Quality in Research: Foes or Friends?
https://doi.org/10.1097/md.0000000000022811 Systemic treatment of a metastatic carotid body tumor
https://doi.org/10.1016/j.jalz.2015.02.002 Boosting translational research on Alzheimer's disease in Europe: The Innovative Medicine Initiative AD research platform
https://doi.org/10.1016/j.vaccine.2022.10.048 Strategic silences, eroded trust: The impact of divergent COVID-19 vaccine sentiments on healthcare workers' relations with peers and patients
https://doi.org/10.1137/20m1357500 Choose Your Path Wisely: Gradient Descent in a Bregman Distance Framework
https://doi.org/10.1200/jco.22.02430 Combination Early-Phase Trials of Anticancer Agents in Children and Adolescents
https://doi.org/10.1016/s1470-2045(24)00312-7 Ending financial discrimination for cancer survivors: embedding the Right to be Forgotten in legislation across Europe
https://doi.org/10.1111/cts.12556 Global Standards to Expedite Learning From Medical Research Data
https://doi.org/10.18848/2154-8587/cgp/v10i03/29-54 An Analysis of the Embodied Energy and Embodied Carbon of Refugee Shelters Worldwide
https://doi.org/10.1177/15553434221125092 How Can Authorities Support Distributed Improvisation During Major Crises? A Study of Decision Bottlenecks Arising During Local COVID-19 Vaccine Roll-Out
https://doi.org/10.1038/s41591-024-03363-2 Using a sex- and gender-informed lens to enhance care in Parkinson’s disease
https://doi.org/10.1016/j.jpain.2025.104777 Placebo nonresponders: An experimental investigation on their unreliability over time
https://doi.org/10.1007/s00204-025-03982-9 The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals
https://doi.org/10.3390/jmahp13010006 Avoiding Error and Finding the Right Balance in European Health Technology Assessments: Insights Generated by the European Access Academy
https://doi.org/10.3389/fpls.2025.1629832 Unlocking seagrass germination: divergent roles of strigolactones and smoke-water in Zostera marina (Zosteraceae)
https://doi.org/10.1002/med.70004 Recent Progress in the Discovery of Anti‐Mpox Agents
https://doi.org/10.1021/acs.jmedchem.5c01695 Exploring the HIV-1 Reverse Transcriptase p51/p66 Interface: Structure-Based Design and Optimization of Novel 2,4,6-Trisubstituted Pyrimidines as Potent NNRTIs with Improved Resistance Profiles
https://doi.org/10.1021/acs.jmedchem.5c02211 Structure- and Privileged Fragment-Based Iterative Optimization: Discovery of 2,4-Disubstituted-6-aminopyrimidines as Novel HIV-1 NNRTIs with Potent Activity against Drug-Resistant Strains and Favorable Safety Profiles
https://doi.org/10.1016/j.pscia.2025.100100 Convergence of computer-aided drug discovery and artificial intelligence: Towards next-generation therapeutics
https://doi.org/10.1080/10572317.2001.10762556 Empowerment and Governance through Information and Communication Technologies: Women’s Perspective
https://doi.org/10.1056/nejmp1401444 Fostering Responsible Data Sharing through Standards
https://doi.org/10.1086/597516 The Taiwanese-American Occultation Survey: The Multi-Telescope Robotic Observatory
https://doi.org/10.1074/jbc.m114.574061 The Role of a Novel Auxiliary Pocket in Bacterial Phenylalanyl-tRNA Synthetase Druggability
https://doi.org/10.1039/c6md00088f Development and design of the tertiary amino effect reaction for DNA-encoded library synthesis
https://doi.org/10.1039/c4sc03218g Highly enantioselective access to diketopiperazines via cinchona alkaloid catalyzed Michael additions
https://doi.org/10.1039/c5md00589b Scaffold morphing leading to evolution of 2,4-diaminoquinolines and aminopyrazolopyrimidines as inhibitors of the ATP synthesis pathway
https://doi.org/10.18063/jmds.2015.01.011 EUPATI: Collaboration between patients, academia and industry to champion the informed patient in the research and development of medicines
https://doi.org/10.1039/c6py00478d Enhanced cytocompatibility and functional group content of poly(l-lysine) dendrimers by grafting with poly(oxazolines)
https://doi.org/10.1371/journal.pone.0070236 IL-17A Mediates Early Post-Transplant Lesions after Heterotopic Trachea Allotransplantation in Mice
https://doi.org/10.2147/copd.s127146 Colds as predictors of the onset and severity of COPD exacerbations
https://doi.org/10.1089/bio.2019.0092 Towards Harmonized Biobanking for Biomonitoring: A Comparison of Human Biomonitoring-Related and Clinical Biorepositories
https://doi.org/10.1586/erp.12.59 Improving R&D productivity of pharmaceutical companies through public–private partnership: experiences from the Innovative Medicines Initiative
https://doi.org/10.26508/lsa.201900461 Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion
https://doi.org/10.1038/nbt.3305 Benchmarking the scientific output of the Innovative Medicines Initiative
https://doi.org/10.1016/j.neuroimage.2020.117217 Characterization of the inflammatory post-ischemic tissue by full volumetric analysis of a multimodal imaging dataset
Improvement of the Ladybug-tools microclimate workflow: A verification study
https://doi.org/10.1016/j.vaccine.2022.07.032 The quest for more effective vaccine markets – Opportunities, challenges, and what has changed with the SARS-CoV-2 pandemic
https://doi.org/10.1002/qua.26769 Relativistic corrections of the electric field gradient in dihalogen molecules XY (X, Y = F, Cl, Br, I, At) within the linear response elimination of the small component formalism
https://doi.org/10.3389/fpubh.2024.1417684 What public health challenges and unmet medical needs would benefit from interdisciplinary collaboration in the EU? A survey and multi-stakeholder debate
https://doi.org/10.1038/nrd3078-c1 Measuring the value of public–private partnerships in the pharmaceutical sciences
https://doi.org/10.1109/tabletop.2008.4660191 System design for the WeSpace: Linking personal devices to a table-centered multi-user, multi-surface environment
https://doi.org/10.1039/c3dt50757b Synthesis of metal selenide colloidal nanocrystals by the hot injection of selenium powder
https://doi.org/10.1177/2168479015618697 Medicines Adaptive Pathways to Patients (MAPPs): A Story of International Collaboration Leading to Implementation
https://doi.org/10.18063/jmds.2015.01.009 The European lead factory—an experiment in collaborative drug discovery
https://doi.org/10.1109/nssmic.2014.7430963 High throughput CUDA implementation of accurate geometric modelling for iterative reconstruction of PET data
https://doi.org/10.3934/jcd.2019009 Deep learning as optimal control problems: Models and numerical methods
https://doi.org/10.1016/j.neuron.2014.10.006 Public-Private Partnership: A New Engine for Translational Research in Neurosciences
https://doi.org/10.3389/fmed.2020.00036 Improving Patient Involvement in the Lifecycle of Medicines: Insights From the EUPATI BE Survey
A methodology For Modelling Microclimate: A Ladybug-tools and ENVI-met Verification Study
https://doi.org/10.17863/cam.101654 Classification of datasets with imputed missing values: does imputation quality matter?
https://doi.org/10.18063/jmds.v1i1.122 EUPATI: Collaboration between patients, academia and industry to champion the informed patient in the research and development of medicines
https://doi.org/10.1016/j.csbj.2025.03.019 Going digital to boost safe and sustainable materials innovation markets. The digital safe-and-sustainability-by-design innovation approach of the PINK project
https://doi.org/10.1126/scitranslmed.3007990 New Frontiers for Collaborative Research
https://doi.org/10.1002/biot.201400487 Editorial: The Innovative Medicines Initiative – collaborations are key to innovating R&D processes
https://doi.org/10.1002/eji.201370024 The Innovative Medicines Initiative moves translational immunology forward
https://doi.org/10.1137/17m1111528 Network Modularity in the Presence of Covariates
https://doi.org/10.3109/00498254.2015.1006301 Pharmacokinetics of the natural antibiotic negamycin
https://doi.org/10.6084/m9.figshare.8977556 Improving the thermal comfort in new shelters