Publications in OpenAlex of which a co-author is affiliated to this organization
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| Title | DOI |
|---|---|
| https://doi.org/10.1021/acs.jmedchem.7b00974 | Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate |
| https://doi.org/10.1007/s00262-018-2258-1 | Soluble CTLA-4 as a favorable predictive biomarker in metastatic melanoma patients treated with ipilimumab: an Italian melanoma intergroup study |
| https://doi.org/10.1158/1535-7163.mct-17-1104 | Characterization of the Selective Indoleamine 2,3-Dioxygenase-1 (IDO1) Catalytic Inhibitor EOS200271/PF-06840003 Supports IDO1 as a Critical Resistance Mechanism to PD-(L)1 Blockade Therapy |
| https://doi.org/10.1158/2326-6066.cir-19-0041 | Inhibition of Tryptophan-Dioxygenase Activity Increases the Antitumor Efficacy of Immune Checkpoint Inhibitors |
| https://doi.org/10.1158/1535-7163.mct-20-0464 | Restoration of T-cell Effector Function, Depletion of Tregs, and Direct Killing of Tumor Cells: The Multiple Mechanisms of Action of a-TIGIT Antagonist Antibodies |
| https://doi.org/10.1016/j.nbd.2020.105162 | PPAR gamma agonist leriglitazone improves frataxin-loss impairments in cellular and animal models of Friedreich Ataxia |
| https://doi.org/10.1016/j.jcyt.2022.03.007 | Patient access to and ethical considerations of the application of the European Union hospital exemption rule for advanced therapy medicinal products |
| https://doi.org/10.3390/ijms24043201 | Development of PPARγ Agonists for the Treatment of Neuroinflammatory and Neurodegenerative Diseases: Leriglitazone as a Promising Candidate |
| https://doi.org/10.1038/s41467-024-51884-8 | Cannabidiol ameliorates mitochondrial disease via PPARγ activation in preclinical models |
| https://doi.org/10.1038/s41590-025-02153-3 | Inhibition of ENT1 relieves intracellular adenosine-mediated T cell suppression in cancer |
| https://doi.org/10.1038/s41467-024-50827-7 | Structure elucidation of a human melanocortin-4 receptor specific orthosteric nanobody agonist |
| https://doi.org/10.1021/acs.jmedchem.4c02225 | Discovery, Optimization, and Preclinical Pharmacology of EP652, a METTL3 Inhibitor with Efficacy in Liquid and Solid Tumor Models |
| https://doi.org/10.20517/2394-4722.2018.10 | The combined analysis of solid and liquid biopsies provides additional clinical information to improve patient care |
| https://doi.org/10.1016/j.bone.2013.01.005 | Decreased pool of mesenchymal stem cells is associated with altered chemokines serum levels in atrophic nonunion fractures |
| https://doi.org/10.1016/j.gie.2016.08.007 | Safety and feasibility of an endoluminal-suturing device for endoscopic gastric reduction (with video) |
| https://doi.org/10.1097/corr.0000000000001107 | Did Osteoblastic Cell Therapy Improve the Prognosis of Pre-fracture Osteonecrosis of the Femoral Head? A Randomized, Controlled Trial |
| https://doi.org/10.1177/2472555217712659 | Microenvironment Tumor Metabolic Interactions Highlighted by qMSI: Application to the Tryptophan-Kynurenine Pathway in Immuno-Oncology |
| https://doi.org/10.1016/j.ejrad.2017.10.020 | Value of a radiographic score for the assessment of healing of nailed femoral and tibial shaft fractures: A retrospective preliminary study |
| https://doi.org/10.1038/s41467-022-33871-z | Structural insight into Tn3 family transposition mechanism |
| https://doi.org/10.1097/corr.0000000000002610 | Does Adjunction of Autologous Osteoblastic Cells Improve the Results of Core Decompression in Early-stage Femoral Head Osteonecrosis? A Double-blind, Randomized Trial |
| https://doi.org/10.1186/s13287-021-02432-4 | Percutaneous administration of allogeneic bone-forming cells for the treatment of delayed unions of fractures: a pilot study |
| https://doi.org/10.1172/jci157907 | TIGIT inhibition and lenalidomide synergistically promote antimyeloma immune responses after stem cell transplantation in mice |
| https://doi.org/10.1200/jco.2021.39.15_suppl.2562 | Phase 1 trial of the adenosine A2A receptor antagonist inupadenant (EOS-850): Update on tolerability, and antitumor activity potentially associated with the expression of the A2A receptor within the tumor. |
| https://doi.org/10.1080/23723556.2020.1804308 | PNP inhibitors selectively kill cancer cells lacking SAMHD1 |
| https://doi.org/10.1186/s12967-023-04622-5 | Mitochondrial modulation with leriglitazone as a potential treatment for Rett syndrome |
| https://doi.org/10.1038/s44319-023-00013-5 | The olfactory receptor Olfr78 promotes differentiation of enterochromaffin cells in the mouse colon |
| https://doi.org/10.1016/j.jconrel.2022.11.055 | Inhaled dry powder cisplatin increases antitumour response to anti-PD1 in a murine lung cancer model |
| https://doi.org/10.1111/bph.16361 | Radiprodil, a selective GluN2B negative allosteric modulator, rescues audiogenic seizures in mice carrying the GluN2A(N615S) mutation |
| https://doi.org/10.1186/s12891-021-04750-3 | Safety and efficacy of a single intra-articular injection of a novel enhanced protein solution (JTA-004) compared to hylan G-F 20 in symptomatic knee osteoarthritis: a randomized, double-blind, controlled phase II/III study |
| https://doi.org/10.1021/acs.oprd.2c00360 | Establishing Best Practice for the Application and Support of Solubility Purge Factors |
| https://doi.org/10.1186/s12974-024-03017-7 | Increased regulatory activity of intestinal innate lymphoid cells type 3 (ILC3) prevents experimental autoimmune encephalomyelitis severity |
| https://doi.org/10.1055/a-0860-5387 | Endoscopic full-thickness resection using an endoluminal-suturing device: a proof-of-concept study |
| https://doi.org/10.1136/annrheumdis-2016-eular.1502 | THU0540 Autologous Osteoblastic Cells versus Concentrated Bone Marrow Implantation in Osteonecrosis of The Femoral Head: A Randomized Controlled Single Blind Study |
| https://doi.org/10.1021/acs.jmedchem.4c01237 | Discovery of UCB9386: A Potent, Selective, and Brain-Penetrant Nuak1 Inhibitor Suitable for In Vivo Pharmacological Studies |
| https://doi.org/10.3389/fmed.2022.1023224 | A new small molecule DHODH-inhibitor [KIO-100 (PP-001)] targeting activated T cells for intraocular treatment of uveitis — A phase I clinical trial |
| https://doi.org/10.1158/1538-7445.am2023-6282 | Abstract 6282: EP102: Pharmacological inhibition of METTL3 arrests tumor progression and prolongs survival in CDX and PDX models of AML |
| https://doi.org/10.1186/2051-1426-2-s3-p195 | Preclinical assessment of a novel small molecule inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1) |
| https://doi.org/10.3389/fnimg.2023.1142463 | Translocator protein PET imaging in temporal lobe epilepsy: A reliable test-retest study using asymmetry index |
| https://doi.org/10.1158/1538-7445.am2025-3136 | Abstract 3136: EOS-215, a first-in-class TREM2 antagonist, designed to reprogram the tumor microenvironment and overcome resistance |
| https://doi.org/10.1182/blood-2024-208998 | A Phase 1 Study Investigating the Safety and Efficacy of Danvatirsen As Monotherapy Followed By Combination with Venetoclax in Patients with Relapsed/Refractory MDS and AML |
| https://doi.org/10.1016/j.biopha.2025.118553 | Leriglitazone improves iron homeostasis and ferroptotic markers in frataxin-deficient dorsal root ganglia neurons |
| https://doi.org/10.1177/01926233211003866 | Microscope-Based Automated Quantification of Liver Fibrosis in Mice Using a Deep Learning Algorithm |
| https://doi.org/10.1016/j.ejpb.2021.04.018 | The combination of an innovative dry powder for inhalation and a standard cisplatin-based chemotherapy in view of therapeutic intensification against lung tumours |
| https://doi.org/10.1002/lt.26301 | A Mesenchymal‐Epithelial Transition Factor‐Agonistic Antibody Accelerates Cirrhotic Liver Regeneration and Improves Mouse Survival Following Partial Hepatectomy |
| https://doi.org/10.1186/s12967-024-04869-6 | Epigenetic MLH1 silencing concurs with mismatch repair deficiency in sporadic, naturally occurring colorectal cancer in rhesus macaques |
| https://doi.org/10.1016/j.jpba.2019.02.038 | Target exposure and pharmacodynamics study of the indoleamine 2,3-dioxygenase-1 (IDO-1) inhibitor epacadostat in the CT26 mouse tumor model |
| https://doi.org/10.18632/oncotarget.28056 | The antitumoral effects of chemerin are independent from leukocyte recruitment and mediated by inhibition of neoangiogenesis |
| https://doi.org/10.1111/aor.13056 | In Vivo Validation of a Less Invasive Gastrostimulator |
| https://doi.org/10.1158/1538-7445.am2020-ct152 | Abstract CT152: First in human study with EOS100850, a novel potent A2A antagonist, shows excellent tolerance and clinical benefit in immune resistant advanced cancers |
| https://doi.org/10.1016/j.biopha.2021.111716 | Preclinical tolerance evaluation of the addition of a cisplatin-based dry powder for inhalation to the conventional carboplatin-paclitaxel doublet for treatment of non-small cell lung cancer |
| https://doi.org/10.1158/1538-7445.am2021-ct118 | Abstract CT118: Preliminary data from Phase I first-in-human study of EOS884448, a novel potent anti-TIGIT antibody, monotherapy shows favorable tolerability profile and early signsof clinical activity in immune-resistant advanced cancers |
| https://doi.org/10.3390/pharmaceutics15010202 | PPAR Gamma Agonist Leriglitazone Recovers Alterations Due to Pank2-Deficiency in hiPS-Derived Astrocytes |
| https://doi.org/10.1016/j.jcyt.2021.11.007 | Proceedings of the ISCT scientific signature series symposium, “Advances in cell and gene therapies for lung diseases and critical illnesses” |
| https://doi.org/10.1016/j.gie.2013.03.486 | Sa1435 Endomina : the Endoluminal Universal Robotized Triangulation System: Description and Preliminary Results in Isolated Pig Stomach |
| https://doi.org/10.1158/1538-7445.am2018-lb-291 | Abstract LB-291: EOS100850, an insurmountable and non-brain penetrant A2A receptor antagonist, inhibits adenosine-mediated T cell suppression, demonstrates anti-tumor activity and exhibits best-in class characteristics |
| https://doi.org/10.1016/j.bone.2007.04.050 | Treatment of osteonecrosis of the femoral head with implantation of autologous bone-marrow cells: Five-year follow-up |
| https://doi.org/10.1158/1538-7445.am2017-1683 | Abstract 1683: A novel adenosine A2A receptor antagonist optimized for high potency in adenosine-rich tumor microenvironment boosts antitumor immunity |
| https://doi.org/10.1158/1538-7445.am2019-3261 | Abstract 3261: EOS100850, a non-brain penetrant highly selective A2Areceptor antagonist, uniquely maintains high potency within the adenosine rich tumor microenvironment |
| https://doi.org/10.1158/1538-7445.am2018-lb-114 | Abstract LB-114: a-TIGIT antagonist antibody EOS884448 shows dual mechanism of action by restoration of T cell effector functions and preferential depletion of Treg |
| https://doi.org/10.1182/blood-2019-128308 | Expression of the Tigit/CD226/CD155 Receptors/Ligand System in Chronic Lymphocytic Leukemia |
| https://doi.org/10.1182/blood-2019-131493 | Beyond PD-1: Investigating the Therapeutic Potential of TIGIT Blockade in DLBCL |
| https://doi.org/10.1158/1538-7445.am2019-3278 | Abstract 3278: EOS100850 potently restores adenosine A2Areceptor-dependent suppression of T cell function in the adenosine rich tumor microenvironment |
| https://doi.org/10.1158/1538-7445.am2022-lb189 | Abstract LB189: Pharmacodynamic assessment of a-TIGIT mAb EOS-448 highlights multiple FcγR-mediated mode-of-actions in blood and tumor of patients with advanced solid tumors |
| https://doi.org/10.1016/j.jtho.2022.07.593 | EP08.01-021 Phase 2 Study Evaluating Inupadenant in Combination with Chemotherapy in Adults with NSCLC who Progressed on Immunotherapy |
| https://doi.org/10.22541/au.169028585.52171833/v1 | Radiprodil, a selective GluN2B negative allosteric modulator, rescues audiogenic seizures in mice carrying the GluN2A(N615S) mutation |
| https://doi.org/10.1158/1538-7445.am2024-734 | Abstract 734: Inhibition of equilibrative nucleoside transporter 1 relieves intracellular adenosine-mediated immune suppression |
| https://doi.org/10.1016/j.ijpharm.2021.120425 | Pulmonary and renal tolerance of cisplatin-based regimens combining intravenous and endotracheal routes for lung cancer treatment in mice |
| https://doi.org/10.1016/j.igie.2024.04.002 | Feasibility of a fully endoscopic one-anastomosis gastric bypass procedure after endoscopic sleeve gastroplasty in pigs |
| https://doi.org/10.1002/brb3.70350 | Amelioration of Central Nervous System Autoimmunity Through FFAR2 Agonism Is Associated With Changes in Gut Microbiota |
| https://doi.org/10.1172/jci200418688 | Impaired neuromuscular transmission and skeletal muscle fiber necrosis in mice lacking Na/Ca exchanger 3 |
| https://doi.org/10.1016/j.gie.2015.03.861 | Mo1531 Feasibility of Using a Novel Triangulation Device to Perform Flexible Endoscopic Suturing in a Porcine Model |
| https://doi.org/10.18063/jmds.2015.02.004 | Cell therapy for bone fracture repair: A comparative preclinical review of mesenchymal stromal cells from bone marrow and from adipose tissue |
| https://doi.org/10.4155/bio-2016-0062 | Discovery Bioanalysis and In Vivo Pharmacology as an Integrated Process: A Case Study in Oncology Drug Discovery |
| https://doi.org/10.1016/j.gie.2016.03.743 | Mo2052 Safety and Feasibility of an Endoluminal-Suturing Device (Endomina®) As an Aid for Endoscopic Gastric Reduction |
| https://doi.org/10.1016/j.joca.2020.02.248 | Efficacy and safety of intra-articular injection of JTA-004, a novel supplemented protein solution, in osteoarthritic knee pain |
| https://doi.org/10.1158/1538-7445.sabcs18-4149 | Abstract 4149: Extensive characterization of the adenosine pathway in human solid tumors gives a hint on cancer indication selection for the A2Areceptor antagonist EOS100850 |
| https://doi.org/10.1016/j.jcyt.2017.03.007 | Welcome to ISCT 2017 London |
| https://doi.org/10.1158/1538-7445.am2019-4147 | Abstract 4147: EOS100850, an A2Areceptor antagonist with prolonged pharmacodynamic activity, mediates the generation ofspecific durable immune responses in a murine breast cancer model |
| https://doi.org/10.1016/j.jcyt.2020.04.055 | ALLOB, an off-the-shelf allogeneic bone-forming cell therapy product derived from BMSC displays bone regenerative property and improves bone healing |
| https://doi.org/10.1136/annrheumdis-2020-eular.1961 | FRI0400 EFFICACY AND SAFETY OF AN INTRA-ARTICULAR INJECTION OF JTA-004, A NOVEL ENHANCED PROTEIN SOLUTION, IN KNEE OSTEOARTHRITIS PAIN: A RANDOMISED, DOUBLE-BLIND CONTROLLED PHASE II/III STUDY |
| https://doi.org/10.1158/1538-7445.am2019-3249 | Abstract 3249: a-TIGIT mediates antitumor activity through multiple mechanisms of action involving activation of intratumor effector T cells and depletion of regulatory T cells |
| https://doi.org/10.1200/jco.2022.40.16_suppl.tps9158 | Randomized phase 2 study evaluating efficacy and safety of inupadenant in combination with chemotherapy in adults with metastatic non–small cell lung cancer (mNSCLC) who progressed on immunotherapy. |
| https://doi.org/10.1158/1538-7445.am2023-4135 | Abstract 4135: A novel plasma cell-based mechanism of action of adenosine immunomodulation and A2AR antagonism |
| https://doi.org/10.1055/a-2185-5947 | Pilot study of an endoluminal-suturing device as a treatment for patients with gastroesophageal reflux disease |
| https://doi.org/10.1136/jitc-2023-sitc2023.0074 | 74 Abstract withdrawn |
| https://doi.org/10.1097/00008469-199409000-00004 | Assessment of the new immunological test Hemoblot for detecting occult blood in faeces |
| https://doi.org/10.1016/j.bone.2007.04.051 | Treatment of osteonecrosis of the femoral head with implantation of preosteoblastic cells into the necrotic zone: Case report |
| https://doi.org/10.1016/j.bone.2007.04.013 | Use of total body MRI for the diagnosis of multifocal ON lesions: Case report |
| Le miconazole sous le kaléïdoscope. | |
| https://doi.org/10.1530/boneabs.5.p159 | Osteogenic superiority of bone marrow-derived osteoblastic cells (ALLOB(R)) over bone marrow-derived mesenchymal stromal cells |
| https://doi.org/10.1158/2326-6066.imm2016-b030 | Abstract B030: Development and validation of a phenotypic screening platform for the identification of novel immuno-oncology targets |
| https://doi.org/10.1016/s1169-8330(16)30208-3 | Ostéoblastes autologues (PREOB®) versus concentré de moelle autologue dans l’ostéonécrose de la tête fémorale au stade préfracturaire : étude randomisée |
| https://doi.org/10.1158/1538-7445.am2017-4612 | Abstract 4612: Development and validation of a screening platform for the identification of novel immuno-oncology targets |
| https://doi.org/10.1016/j.dmpk.2017.11.102 | Biomarker monitoring by quantitative maldi imaging: Application to the tryptophan-kynurenine pathway in immuno-oncology |
| Morphological assessment of non-human primate models of osteoarthritis using HR-MRI and μCT arthrography | |
| https://doi.org/10.1158/1538-7445.sabcs18-4154 | Abstract 4154: EOS100850 inhibits A2Areceptor signaling in human whole blood: Two pharmacodynamic assays to monitor EOS100850 activity in clinical studies |
| https://doi.org/10.1158/1538-7445.sabcs18-3278 | Abstract 3278: EOS100850 potently restores adenosine A2Areceptor-dependent suppression of T cell function in the adenosine rich tumor microenvironment |
| https://doi.org/10.1158/1538-7445.am2019-4149 | Abstract 4149: Extensive characterization of the adenosine pathway in human solid tumors gives a hint on cancer indication selection for the A2A receptor antagonist EOS100850 |
| https://doi.org/10.1158/1538-7445.sabcs18-4969 | Abstract 4969: TIGIT pathway phenotyping sheds light on promising strategies to restore anti-tumor immunity |
| https://doi.org/10.1158/1538-7445.am2019-3240 | Abstract 3240: EOS884448, a high affinity fully human antibody directed against TIGIT, mediates in vitro anti-tumor activity through multiples mechanisms of action involving activation of intratumor effector cells and depletion of regulatory T cells |