Ludwig Cancer Research

Publications in OpenAlex of which a co-author is affiliated to this organization

All publications | By field | By subfield

All publications [Next]
Title DOI
https://doi.org/10.1007/s00401-016-1545-1 The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
https://doi.org/10.1038/nature03546 A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
https://doi.org/10.1126/science.1840703 A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma
https://doi.org/10.1038/nrc864 Live or let die: the cell's response to p53
https://doi.org/10.1038/nature05610 Patterns of somatic mutation in human cancer genomes
https://doi.org/10.1200/jco.2009.23.9764 Pazopanib in Locally Advanced or Metastatic Renal Cell Carcinoma: Results of a Randomized Phase III Trial
https://doi.org/10.1038/nm934 Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase
https://doi.org/10.1038/nrc1456 High interstitial fluid pressure — an obstacle in cancer therapy
https://doi.org/10.1038/nrm2183 Molecular regulation of angiogenesis and lymphangiogenesis
https://doi.org/10.1038/nrm1128 ROCKs: multifunctional kinases in cell behaviour
https://doi.org/10.1146/annurev.iy.08.040190.001345 Interleukin-6: An Overview
https://doi.org/10.1126/science.aah5043 Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine
https://doi.org/10.1016/0092-8674(95)90404-2 Dimerization of cell surface receptors in signal transduction
https://doi.org/10.1038/nature06881 The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
https://doi.org/10.1042/bj3460561 The PI3K–PDK1 connection: more than just a road to PKB
https://doi.org/10.1016/s1470-2045(05)70101-7 Prophylactic quadrivalent human papillomavirus (types 6, 11, 16, and 18) L1 virus-like particle vaccine in young women: a randomised double-blind placebo-controlled multicentre phase II efficacy trial
https://doi.org/10.1038/ni1013 Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins
https://doi.org/10.1016/s0896-6273(00)80272-x ALS-Linked SOD1 Mutant G85R Mediates Damage to Astrocytes and Promotes Rapidly Progressive Disease with SOD1-Containing Inclusions
https://doi.org/10.1038/nature04480 Lymphangiogenesis in development and human disease
https://doi.org/10.1146/annurev.iy.12.040194.002005 Tumor Antigens Recognized by T Lymphocytes
https://doi.org/10.4049/jimmunol.179.3.1969 Exosomes with Immune Modulatory Features Are Present in Human Breast Milk
https://doi.org/10.1038/nri1309 NKT cells: what's in a name?
https://doi.org/10.1038/ni.1659 Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset
https://doi.org/10.1146/annurev.immunol.22.012703.104538 CELL BIOLOGY OF ANTIGEN PROCESSING IN VITRO AND IN VIVO
https://doi.org/10.1038/nrc3670 Tumour antigens recognized by T lymphocytes: at the core of cancer immunotherapy
https://doi.org/10.1021/ac9810516 Role of Accurate Mass Measurement (±10 ppm) in Protein Identification Strategies Employing MS or MS/MS and Database Searching
https://doi.org/10.1126/science.276.5310.248 Dopamine Neuron Agenesis in Nurr1-Deficient Mice
https://doi.org/10.1126/science.1086071 Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice
https://doi.org/10.1016/0304-3835(87)90157-1 Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: Preliminary findings
https://doi.org/10.1016/j.cell.2006.09.039 The Conserved KMN Network Constitutes the Core Microtubule-Binding Site of the Kinetochore
https://doi.org/10.1016/s0092-8674(03)00115-6 Centromeres and Kinetochores
https://doi.org/10.1158/2159-8290.cd-13-0642 Acquired Resistance and Clonal Evolution in Melanoma during BRAF Inhibitor Therapy
https://doi.org/10.1038/nature10442 CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing
https://doi.org/10.1084/jem.178.2.489 The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas.
https://doi.org/10.1038/ni1376 Interleukin 27 negatively regulates the development of interleukin 17–producing T helper cells during chronic inflammation of the central nervous system
https://doi.org/10.1038/nrm2310 Molecular architecture of the kinetochore–microtubule interface
https://doi.org/10.1084/jem.180.1.35 A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas.
https://doi.org/10.1038/nrm2718 Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis
https://doi.org/10.1038/s41577-020-0406-2 Lactate modulation of immune responses in inflammatory versus tumour microenvironments
https://doi.org/10.1006/excr.1999.4701 Signaling by Distinct Classes of Phosphoinositide 3-Kinases
https://doi.org/10.1002/art.1780310614 Interleukin‐6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides
https://doi.org/10.1084/jem.183.3.725 Human tumor antigens recognized by T lymphocytes.
https://doi.org/10.1200/jco.2006.07.1522 Definition of Clinically Distinct Molecular Subtypes in Estrogen Receptor–Positive Breast Carcinomas Through Genomic Grade
https://doi.org/10.1038/sj.bjc.6603469 High sustained efficacy of a prophylactic quadrivalent human papillomavirus types 6/11/16/18 L1 virus-like particle vaccine through 5 years of follow-up
https://doi.org/10.1038/nrc863 Lymphangiogenesis and cancer metastasis
https://doi.org/10.1038/431525b Intragenic ERBB2 kinase mutations in tumours
https://doi.org/10.1002/(sici)1097-0215(19990118)80:2<219::aid-ijc10>3.0.co;2-s Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by geneMAGE-3 and presented by HLA-A1
https://doi.org/10.1016/s1074-7613(00)80426-4 Characterization of an Antigen That Is Recognized on a Melanoma Showing Partial HLA Loss by CTL Expressing an NK Inhibitory Receptor
https://doi.org/10.1084/jem.179.3.921 Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes.
https://doi.org/10.1016/s0962-8924(01)02153-5 Rho family proteins: coordinating cell responses
https://doi.org/10.1038/nature05010 Mast cells are essential intermediaries in regulatory T-cell tolerance
https://doi.org/10.1016/j.ccr.2006.12.003 Aneuploidy Acts Both Oncogenically and as a Tumor Suppressor
https://doi.org/10.1016/s0304-419x(98)00015-8 Signal transduction via platelet-derived growth factor receptors
https://doi.org/10.1016/s0021-9258(17)32506-1 Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4.
https://doi.org/10.1038/342955a0 Style self-incompatibility gene products of Nicotlana alata are ribonucleases
https://doi.org/10.1038/338557a0 Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor
https://doi.org/10.1084/jem.176.5.1453 A nonapeptide encoded by human gene MAGE-1 is recognized on HLA-A1 by cytolytic T lymphocytes directed against tumor antigen MZ2-E.
https://doi.org/10.1158/0008-5472.can-12-0569 Tryptophan Catabolism in Cancer: Beyond IDO and Tryptophan Depletion
https://doi.org/10.1038/362553a0 Human lysozyme gene mutations cause hereditary systemic amyloidosis
https://doi.org/10.1016/j.tig.2005.10.003 Rapid evolution of noncoding RNAs: lack of conservation does not mean lack of function
Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth.
https://doi.org/10.1146/annurev.immunol.24.021605.090733 HUMAN T CELL RESPONSES AGAINST MELANOMA
https://doi.org/10.1093/annonc/mdv177 Circulating tumor DNA as an early marker of therapeutic response in patients with metastatic colorectal cancer
https://doi.org/10.1038/ncb1905 A SNAIL1–SMAD3/4 transcriptional repressor complex promotes TGF-β mediated epithelial–mesenchymal transition
https://doi.org/10.1016/s0952-7915(97)80050-7 T cell defined tumor antigens
https://doi.org/10.1172/jci23373 Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909
https://doi.org/10.1016/j.ijrobp.2013.12.012 Local Recurrence After Complete Clinical Response and Watch and Wait in Rectal Cancer After Neoadjuvant Chemoradiation: Impact of Salvage Therapy on Local Disease Control
https://doi.org/10.1128/mcb.20.24.9138-9148.2000 Forkhead Transcription Factor FKHR-L1 Modulates Cytokine-Dependent Transcriptional Regulation of p27KIP1
https://doi.org/10.1016/j.semcancer.2005.05.002 Three-dimensional tissue culture models in cancer biology
https://doi.org/10.1038/s42255-020-00317-z Metabolites and the tumour microenvironment: from cellular mechanisms to systemic metabolism
https://doi.org/10.1073/pnas.87.21.8602 Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas.
https://doi.org/10.1007/bf01246677 Structure, chromosomal localization, and expression of 12 genes of the MAGE family
https://doi.org/10.1128/mcb.19.11.7327 DNA Methylation Is the Primary Silencing Mechanism for a Set of Germ Line- and Tumor-Specific Genes with a CpG-Rich Promoter
https://doi.org/10.1074/jbc.272.5.2927 The Enhanced Tumorigenic Activity of a Mutant Epidermal Growth Factor Receptor Common in Human Cancers Is Mediated by Threshold Levels of Constitutive Tyrosine Phosphorylation and Unattenuated Signaling
https://doi.org/10.1016/s1074-7613(95)80053-0 BAGE: a new gene encoding an antigen recognized on human melanomas by cytolytic T lymphocytes
https://doi.org/10.1016/j.cell.2009.03.006 Rethinking ALS: The FUS about TDP-43
https://doi.org/10.1146/annurev-cellbio-101011-155718 Cytokinesis in Animal Cells
https://doi.org/10.1073/pnas.1417320112 Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patients
https://doi.org/10.1084/jem.182.3.689 A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma.
https://doi.org/10.1016/s0092-8674(00)81365-3 A Complex of NuMA and Cytoplasmic Dynein Is Essential for Mitotic Spindle Assembly
https://doi.org/10.1038/416183a Cbl–CIN85–endophilin complex mediates ligand-induced downregulation of EGF receptors
https://doi.org/10.1073/pnas.1113873109 Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase
https://doi.org/10.1074/jbc.273.33.21145 Identification and Functional Characterization of a Smad Binding Element (SBE) in the JunB Promoter That Acts as a Transforming Growth Factor-β, Activin, and Bone Morphogenetic Protein-inducible Enhancer
https://doi.org/10.1073/pnas.93.14.7149 The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation.
https://doi.org/10.1038/ncb1780 The type I TGF-β receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner
https://doi.org/10.1371/journal.pcbi.1000176 Differentiating Protein-Coding and Noncoding RNA: Challenges and Ambiguities
https://doi.org/10.1172/jci22037 Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation
https://doi.org/10.1172/jci37865 Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice
https://doi.org/10.1016/s0167-5699(97)80020-5 Tumor antigens recognized by T cells
https://doi.org/10.1016/s0165-2478(02)00023-8 Mechanisms of TGF-β signaling in regulation of cell growth and differentiation
https://doi.org/10.1038/onc.2012.347 JAK/STAT signaling in hematological malignancies
https://doi.org/10.1038/ni1045 Notch regulation of lymphocyte development and function
https://doi.org/10.1016/j.febslet.2012.02.037 Regulation of EMT by TGFβ in cancer
https://doi.org/10.1186/gb-2010-11-1-r3 NetPath: a public resource of curated signal transduction pathways
https://doi.org/10.1083/jcb.141.5.1147 A Role for Cdc42 in Macrophage Chemotaxis
https://doi.org/10.1146/annurev-pathol-011110-130324 Glioblastoma: From Molecular Pathology to Targeted Treatment
https://doi.org/10.1016/0092-8674(91)90529-8 Degradation of p53 can be targeted by HPV E6 sequences distinct from those required for p53 binding and trans-activation
https://doi.org/10.1111/j.1755-148x.2010.00757.x Cancer stem cells versus phenotype‐switching in melanoma
https://doi.org/10.1002/j.1460-2075.1991.tb08049.x A role of the latent TGF-beta 1-binding protein in the assembly and secretion of TGF-beta 1.
https://doi.org/10.1042/0264-6021:3460561 The PI3K‒PDK1 connection: more than just a road to PKB