MSD Europe (Belgium)

Publications in OpenAlex of which a co-author is affiliated to this organization

All publications | By field | By subfield

All publications [Next]
Title DOI
https://doi.org/10.1056/nejmoa0804602 Intensive Lipid Lowering with Simvastatin and Ezetimibe in Aortic Stenosis
https://doi.org/10.1016/s0140-6736(09)61913-9 Effects of high-dose versus low-dose losartan on clinical outcomes in patients with heart failure (HEAAL study): a randomised, double-blind trial
https://doi.org/10.1210/jc.2006-1009 Effect of Single Oral Doses of Sitagliptin, a Dipeptidyl Peptidase-4 Inhibitor, on Incretin and Plasma Glucose Levels after an Oral Glucose Tolerance Test in Patients with Type 2 Diabetes
https://doi.org/10.1177/2168479015580384 Partnering With Patients in the Development and Lifecycle of Medicines: A Call for Action
https://doi.org/10.1016/j.cmet.2007.11.012 The Acyclic CB1R Inverse Agonist Taranabant Mediates Weight Loss by Increasing Energy Expenditure and Decreasing Caloric Intake
https://doi.org/10.1002/pds.1435 A quantitative approach to benefit-risk assessment of medicines – part 1: the development of a new model using multi-criteria decision analysis
https://doi.org/10.1038/mi.2016.74 The nasal mucosal late allergic reaction to grass pollen involves type 2 inflammation (IL-5 and IL-13), the inflammasome (IL-1β), and complement
https://doi.org/10.1111/cts.13048 Safety, tolerability, and pharmacokinetics of single‐ and multiple‐dose administration of islatravir (MK‐8591) in adults without HIV
https://doi.org/10.1080/13696998.2022.2043634 Cost-effectiveness of pembrolizumab for the first-line treatment of patients with unresectable or metastatic MSI-H/dMMR colorectal cancer in the United States
https://doi.org/10.1002/wps.21374 Attention‐deficit/hyperactivity disorder (ADHD) in adults: evidence base, uncertainties and controversies
https://doi.org/10.1186/s12916-024-03322-1 Low awareness of the transitivity assumption in complex networks of interventions: a systematic survey from 721 network meta-analyses
https://doi.org/10.1016/j.ejca.2023.03.015 Health-Related Quality of Life in Patients With Advanced Endometrial Cancer Treated With Lenvatinib Plus Pembrolizumab or Treatment of Physician’s Choice
https://doi.org/10.1016/j.amjcard.2006.10.064 Design and Baseline Characteristics of the Simvastatin and Ezetimibe in Aortic Stenosis (SEAS) Study
https://doi.org/10.1002/cncr.10516 Prevention of cisplatin‐induced acute and delayed emesis by the selective neurokinin‐1 antagonists, L‐758,298 and MK‐869
https://doi.org/10.1177/0269881107082108 Pharmacodynamic and pharmacokinetic effects of MK-0343, a GABAAα2,3subtype selective agonist, compared to lorazepam and placebo in healthy male volunteers
https://doi.org/10.1111/j.1365-2125.2009.03543.x Inhibition of capsaicin‐induced increase in dermal blood flow by the oral CGRP receptor antagonist, telcagepant (MK‐0974)
https://doi.org/10.1177/0269881106072343 Pharmacodynamic and pharmacokinetic effects of TPA023, a GABAAα2,3subtype-selective agonist, compared to lorazepam and placebo in healthy volunteers
https://doi.org/10.1023/a:1017529920916 Electrochemical supercapacitors based on industrial carbon blacks in aqueous H2SO4
https://doi.org/10.1530/eje-11-0751 Prednisone affects inflammation, glucose tolerance, and bone turnover within hours of treatment in healthy individuals
https://doi.org/10.1016/j.amjcard.2010.01.363 Observed and Predicted Reduction of Ischemic Cardiovascular Events in the Simvastatin and Ezetimibe in Aortic Stenosis Trial
https://doi.org/10.1007/s00213-016-4375-x On-the-road driving performance the morning after bedtime use of suvorexant 15 and 30 mg in healthy elderly
https://doi.org/10.1038/ki.2012.210 Losartan and enalapril are comparable in reducing proteinuria in children
https://doi.org/10.1007/bf02956443 A hazard quotient approach for assessing the risk to non-target arthropods from
https://doi.org/10.1007/s00198-016-3503-0 Continuous treatment with odanacatib for up to 8 years in postmenopausal women with low bone mineral density: a phase 2 study
https://doi.org/10.1124/jpet.117.245894 Preclinical to Human Translational Pharmacology of the Novel M1 Positive Allosteric Modulator MK-7622
https://doi.org/10.1002/jrsm.1478 Quantifying the robustness of primary analysis results: A case study on missing outcome data in pairwise and network meta‐analysis
https://doi.org/10.1002/jbmr.3994 Effects of Odanacatib on Bone Structure and Quality in Postmenopausal Women With Osteoporosis: 5-Year Data From the Phase 3 Long-Term Odanacatib Fracture Trial (LOFT) and its Extension
https://doi.org/10.1136/heartjnl-2011-300475 A risk score for predicting mortality in patients with asymptomatic mild to moderate aortic stenosis
https://doi.org/10.1002/jbmr.4284 Incidence of Hip and Subtrochanteric/Femoral Shaft Fractures in Postmenopausal Women With Osteoporosis in the Phase 3 Long-Term Odanacatib Fracture Trial
https://doi.org/10.1111/bcp.12547 Characterizing the PK/PD relationship for inhibition of capsaicin‐induced dermal vasodilatation by MK‐3207, an oral calcitonin gene related peptide receptor antagonist
https://doi.org/10.1016/j.lungcan.2021.03.020 Pembrolizumab+chemotherapy versus atezolizumab+chemotherapy+/−bevacizumab for the first-line treatment of non-squamous NSCLC: A matching-adjusted indirect comparison
https://doi.org/10.3390/cancers12123648 A Matching-Adjusted Indirect Comparison of Pembrolizumab + Chemotherapy vs. Nivolumab + Ipilimumab as First-Line Therapies in Patients with PD-L1 TPS ≥1% Metastatic NSCLC
https://doi.org/10.1177/2042098615579314 A randomized, crossover, placebo-controlled clinical trial to assess the sensitivity of the CRCDS Mini-Sim to the next-day residual effects of zopiclone
https://doi.org/10.1007/s00198-020-05701-9 Randomized, controlled trial to assess the safety and efficacy of odanacatib in the treatment of men with osteoporosis
https://doi.org/10.1128/aac.00931-22 Safety and Pharmacokinetics of Islatravir in Individuals with Severe Renal Insufficiency
https://doi.org/10.1177/0962280220983544 Continuous(ly) missing outcome data in network meta-analysis: A one-stage pattern-mixture model approach
https://doi.org/10.1007/s43441-022-00426-9 Path Forward to Optimise Post-approval Change Management and Facilitate Continuous Supply of Medicines and Vaccines of High Quality Worldwide
https://doi.org/10.1002/cpt.1121 Medicines Adaptive Pathways to Patients: Why, When, and How to Engage?
https://doi.org/10.1002/cpt.2152 Optimizing Pediatric Medicine Developments in the European Union Through Pragmatic Approaches
https://doi.org/10.1093/haschl/qxae060 Quantifying public and private investment in European biopharmaceutical research and development
https://doi.org/10.1016/j.biopsych.2022.02.783 P546. Preclinical Characterization and Phase 1 Evaluation of the Tolerability, Pharmacokinetics, and Enzyme Occupancy of MK-8189, a Novel PDE10A Inhibitor
https://doi.org/10.1016/j.mri.2026.110611 The effect of prolonged glucose infusion on resting-state fMRI signal fluctuations at 7 T
https://doi.org/10.1111/j.1365-2125.2010.03869.x The potent calcitonin gene‐related peptide receptor antagonist, telcagepant, does not affect nitroglycerin‐induced vasodilation in healthy men
https://doi.org/10.1016/j.amjcard.2010.07.042 Impact of Baseline Severity of Aortic Valve Stenosis on Effect of Intensive Lipid Lowering Therapy (from the SEAS Study)
https://doi.org/10.1002/jps.24125 Historical Data Analyses and Scientific Knowledge Suggest Complete Removal of the Abnormal Toxicity Test as a Quality Control Test
https://doi.org/10.2215/cjn.11111113 A Randomized, Open-Label, Dose-Response Study of Losartan in Hypertensive Children
https://doi.org/10.1002/pds.1434 Retracted:A quantitative approach to benefit-risk assessment of medicines — part 2: the practical application of a new model
https://doi.org/10.1126/scitranslmed.abg3684 The PET tracer [ 11 C]MK-6884 quantifies M4 muscarinic receptor in rhesus monkeys and patients with Alzheimer’s disease
https://doi.org/10.1002/jmri.26303 Single MRI‐Based Volumetric Assessment in Clinical Practice Is Associated With MS‐Related Disability
https://doi.org/10.1002/syn.21782 Characterization of the novel GlyT1 PET tracer [18F]MK‐6577 in humans
https://doi.org/10.32920/24282025 Polarisation, Violent Extremism and Resilience in Europe today: An analytical framework
https://doi.org/10.1177/0333102413494272 Lack of hemodynamic interaction between CGRP-receptor antagonist telcagepant (MK-0974) and sumatriptan: Results from a randomized study in patients with migraine
https://doi.org/10.1515/ijcre-2017-0248 Waste-to-energy: Coupling Waste Treatment to Highly Efficient CHP
https://doi.org/10.1097/hjh.0b013e32835022a8 A comparison of the natriuretic and kaliuretic effects of cicletanine and hydrochlorothiazide in prehypertensive and hypertensive humans
https://doi.org/10.1089/met.2012.0005 Extended-Release Niacin/Laropiprant Effects on Lipoprotein Subfractions in Patients with Type 2 Diabetes Mellitus
https://doi.org/10.1016/j.healthpol.2019.05.009 Competition between on-patent medicines in Europe
https://doi.org/10.1002/sim.8207 Participants' outcomes gone missing within a network of interventions: Bayesian modeling strategies
https://doi.org/10.1186/s12874-020-01205-6 Pattern-mixture model in network meta-analysis of binary missing outcome data: one-stage or two-stage approach?
https://doi.org/10.1007/s43441-024-00681-y A Global Industry Survey on Post-Approval Change Management and Use of Reliance
https://doi.org/10.1177/0091270008317591 Multiple‐Dose Pharmacokinetics, Pharmacodynamics, and Safety of Taranabant, a Novel Selective Cannabinoid‐1 Receptor Inverse Agonist, in Healthy Male Volunteers
https://doi.org/10.1136/bmjopen-2013-003033 Shaping medicinal product information: a before and after study exploring physicians’ perspectives on the summary of product characteristics
https://doi.org/10.1016/j.ejheart.2008.07.004 Design of the Heart Failure Endpoint Evaluation of AII-Antagonist Losartan (HEAAL) Study in Patients Intolerant to ACE-Inhibitor
https://doi.org/10.1111/bcp.12131 Pharmacokinetic–pharmacodynamic studies of the 11β‐hydroxysteroid dehydrogenase type 1 inhibitor MK‐0916 in healthy subjects
https://doi.org/10.1128/aac.02142-18 Pharmacokinetic Interactions between the Hepatitis C Virus Inhibitors Elbasvir and Grazoprevir and HIV Protease Inhibitors Ritonavir, Atazanavir, Lopinavir, and Darunavir in Healthy Volunteers
https://doi.org/10.1186/s12874-020-00929-9 Comparison of exclusion, imputation and modelling of missing binary outcome data in frequentist network meta-analysis
https://doi.org/10.1093/annonc/mdz004 Outcomes of patients with the third or higher relapsed classical Hodgkin lymphoma: results from the German Hodgkin Study Group
https://doi.org/10.1016/j.clinthera.2019.10.006 Orphan Medicines for Pediatric Use: A Focus on the European Union
https://doi.org/10.2217/imt-2021-0273 Indirect Comparison of Pembrolizumab Monotherapy Versus Nivolumab + Ipilimumab in First-Line Metastatic Lung Cancer
https://doi.org/10.3389/fmed.2023.1207954 What makes joint assessment procedures attractive to the innovative industry: successes, challenges, and proposed improvements
https://doi.org/10.2217/pmt.13.3 Establishing the Diagnosis of Low Back Pain: Patient Selection for Interventional Pain Medicine
https://doi.org/10.1002/pds.1460 Erratum: A quantitative approach to benefit‐risk assessment of medicines — part 2: the practical application of a new model
https://doi.org/10.1177/2168479017744199 Regional Differences During the ICH Regulatory Consultation Process Between the EU, US, and Japan
https://doi.org/10.1007/s43441-023-00601-6 Pediatric Market Access: A Qualitative Study
https://doi.org/10.1007/978-3-7091-1556-5_5 Adaptive Immunity and Trypanosomiasis-Driven B-Cell Destruction
https://doi.org/10.1007/s00198-022-06406-x Effects of odanacatib on bone-turnover markers in osteoporotic postmenopausal women: a post hoc analysis of the LOFT study
https://doi.org/10.2217/fon-2023-0006 Clinical outcomes for previously treated patients with advanced biliary tract cancer: a meta-analysis
https://doi.org/10.1186/s12916-021-02195-y How robust are findings of pairwise and network meta-analysis in the presence of missing participant outcome data?
https://doi.org/10.1002/nbm.70026 Reproducibility of the Determination of 13C‐Labeling of Glutamate and Glutamine in the Human Brain Using selPOCE‐MRS at 7 T Upon [U‐13C]–Labeled Glucose Infusion
https://doi.org/10.1080/13696998.2025.2530862 Cost-effectiveness analysis of pembrolizumab as an adjuvant treatment of early-stage non-small cell lung cancer following complete resection and platinum-based chemotherapy in Canada
https://doi.org/10.1038/hr.2009.42 Effectiveness of open-label losartan/hydrochlorothiazide combination therapy in Asian patients with hypertension not controlled with ACE inhibitor or ARB monotherapy
https://doi.org/10.1126/science.1242563 A U.K. View on the U.S. Attack on Social Sciences
https://doi.org/10.1016/s1556-0864(18)30462-3 188P Treatment switching–adjusted overall survival (OS) in KEYNOTE-024: First-line pembrolizumab versus chemotherapy in patients with advanced non-small cell lung cancer (NSCLC)
https://doi.org/10.1136/bmjopen-2021-058146 Exploratory analyses of clinical trial data used for health technology assessments: a retrospective evaluation
https://doi.org/10.1161/circulationaha.111.045203 Response to Letters Regarding Article, “Outcome of Patients With Low-Gradient “Severe” Aortic Stenosis and Preserved Ejection Fraction”
https://doi.org/10.1016/j.annonc.2022.04.038 20MO Time to deterioration in quality of life in patients (pts) with advanced endometrial cancer (aEC) treated with lenvatinib plus pembrolizumab (L+P) or treatment of physician’s choice (TPC)
https://doi.org/10.1080/08957959408201662 High pressure equipment for the food industry
https://doi.org/10.1097/00000658-198411000-00021 Letter to the Editor
https://doi.org/10.1016/s0140-6736(10)60475-8 High-dose versus low-dose losartan in patients with heart failure – Authors' reply
Cost-Effectiveness Analysis of a Quadrivalent Hpv-(6,11,16&18) Vaccine: Adaptation and Calibration of a Markov Model to Germany
https://doi.org/10.1136/annrheumdis-2019-eular.3682 SAT0363 ENTHESITIS BUT NOT DACTYLITIS CONTRIBUTES TO BURDEN OF DISEASE IN PSA PATIENTS: DATA FROM THE BEPAS REAL LIFE COHORT
https://doi.org/10.1016/s2055-6640(20)31089-x P2 A single monotherapy dose of MK-8591, a novel NRTI, suppresses HIV for 10 days
https://doi.org/10.1016/j.jtho.2020.10.067 MO01.19 An Indirect Comparison of Pembrolizumab Monotherapy Versus Ipilimumab+Nivolumab for First-Line Metastatic NSCLC with PD-L1 TPS≥1%
https://doi.org/10.1016/j.jtho.2020.10.068 MO01.20 Pembrolizumab+Chemo versus Atezolizumab+Chemo+/-Bevacizumab for First-Line Nonsquamous NSCLC: A Matching-Adjusted Indirect Comparison
https://doi.org/10.1016/j.jtho.2020.10.066 MO01.18 An indirect Comparison of Pembrolizumab+Chemo vs Ipilimumab+Nivolumab as First-Line Therapies in Patients with PD-L1 TPS≥1% Metastatic NSCLC
https://doi.org/10.1007/s43441-021-00303-x Oncology Products in the European Union: An Analysis of Regulatory Approvals with a CHMP Oral Explanation
https://doi.org/10.1016/s0167-2991(09)60412-2 The Point of View of the Automobile Industry Prevention is better than cure
https://doi.org/10.21203/rs.3.rs-39035/v3 Pattern-mixture model in network meta-analysis of binary missing outcome data: one-stage or two-stage approach?
https://doi.org/10.21203/rs.3.rs-39035/v2 Pattern-mixture model in network meta-analysis of binary missing outcome data: one-stage or two-stage approach?
https://doi.org/10.21203/rs.3.rs-39035/v1 Pattern-mixture model in network meta-analysis of binary missing outcome data: one-stage or two-stage approach?
https://doi.org/10.1108/978-1-80382-819-020231004 The Impact of COVID-19 Pandemic on the Rights of Persons With Intellectual Disabilities: Evidence From Disability and Self-Advocates Organisations in Europe