Publications in OpenAlex of which a co-author is affiliated to this organization
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| Title | DOI |
|---|---|
| https://doi.org/10.1016/j.cmet.2020.03.009 | Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis |
| https://doi.org/10.1136/jitc-2020-001749 | Therapeutic depletion of CCR8+ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy |
| https://doi.org/10.1016/j.ccell.2022.11.002 | Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop |
| https://doi.org/10.1016/j.tem.2021.10.008 | Common pathways in dementia and diabetic retinopathy: understanding the mechanisms of diabetes-related cognitive decline |
| https://doi.org/10.1016/j.preteyeres.2018.10.006 | The role of placental growth factor (PlGF) and its receptor system in retinal vascular diseases |
| https://doi.org/10.1007/s00125-020-05218-0 | Single-cell transcriptome analysis of the Akimba mouse retina reveals cell-type-specific insights into the pathobiology of diabetic retinopathy |
| https://doi.org/10.1167/iovs.18-25372 | Longitudinal In Vivo Characterization of the Streptozotocin-Induced Diabetic Mouse Model: Focus on Early Inner Retinal Responses |
| https://doi.org/10.1016/j.preteyeres.2021.100966 | Targeting RGD-binding integrins as an integrative therapy for diabetic retinopathy and neovascular age-related macular degeneration |
| https://doi.org/10.1038/s41514-021-00077-4 | The killifish visual system as an in vivo model to study brain aging and rejuvenation |
| https://doi.org/10.1158/1078-0432.ccr-22-1169 | A Phase I Trial of TB-403 in Relapsed Medulloblastoma, Neuroblastoma, Ewing Sarcoma, and Alveolar Rhabdomyosarcoma |
| https://doi.org/10.1111/acel.13537 | The age factor in optic nerve regeneration: Intrinsic and extrinsic barriers hinder successful recovery in the short‐living killifish |
| https://doi.org/10.1016/j.xops.2021.100040 | Phase 1 Study of THR-687, a Novel, Highly Potent Integrin Antagonist for the Treatment of Diabetic Macular Edema |
| https://doi.org/10.1016/j.exer.2018.11.022 | The potent small molecule integrin antagonist THR-687 is a promising next-generation therapy for retinal vascular disorders |
| https://doi.org/10.1016/j.ebiom.2022.104195 | Dysregulation of the kallikrein-kinin system in bronchoalveolar lavage fluid of patients with severe COVID-19 |
| https://doi.org/10.1002/glia.23875 | Tightening the retinal glia limitans attenuates neuroinflammation after optic nerve injury |
| https://doi.org/10.1111/aos.14480 | Phase I trial on robot assisted retinal vein cannulation with ocriplasmin infusion for central retinal vein occlusion |
| https://doi.org/10.1167/tvst.10.14.28 | Phase 1 Dose-Escalation Study of Plasma Kallikrein Inhibitor THR-149 for the Treatment of Diabetic Macular Edema |
| https://doi.org/10.1097/iae.0000000000002599 | PATIENT-REPORTED VISUAL FUNCTION FROM THE OCRIPLASMIN FOR TREATMENT FOR SYMPTOMATIC VITREOMACULAR ADHESION, INCLUDING MACULAR HOLE (OASIS) STUDY |
| https://doi.org/10.1007/s00249-021-01554-0 | A novel assay based on pre-equilibrium titration curves for the determination of enzyme inhibitor binding kinetics |
| https://doi.org/10.1007/s10928-021-09774-9 | Systemic exposure following intravitreal administration of therapeutic agents: an integrated pharmacokinetic approach. 2. THR-687 |
| https://doi.org/10.1111/j.1755-3768.2019.5291 | Cell‐type specific insights into the pathobiology of advanced diabetic retinopathy using single‐cell transcriptome analysis of the Akimba retina |
| https://doi.org/10.1080/02713683.2019.1614197 | The Placental Growth Factor Pathway and Its Potential Role in Macular Degenerative Disease |
| https://doi.org/10.1097/iae.0000000000002862 | OCRIPLASMIN FOR VITREOMACULAR TRACTION IN CLINICAL PRACTICE |
| https://doi.org/10.1080/02713683.2020.1862239 | Heparanase Deficiency Is Associated with Disruption, Detachment, and Folding of the Retinal Pigment Epithelium |
| https://doi.org/10.1167/iovs.62.13.18 | Targeting Plasma Kallikrein With a Novel Bicyclic Peptide Inhibitor (THR-149) Reduces Retinal Thickening in a Diabetic Rat Model |
| https://doi.org/10.1371/journal.pone.0270120 | Calculating the individual probability of successful ocriplasmin treatment in eyes with vitreomacular traction–Validation and refinement of a multivariable prediction model |
| https://doi.org/10.1016/j.exer.2020.108108 | The retinal tyrosine kinome of diabetic Akimba mice highlights potential for specific Src family kinase inhibition in retinal vascular disease |
| https://doi.org/10.18502/jovr.v16i1.8250 | Prognostic Factors Associated with Ocriplasmin Efficacy for the Treatment of Symptomatic Vitreomacular Adhesion and Full-thickness Macular Hole: Analysis from Four Studies |
| https://doi.org/10.1038/s41598-021-03509-z | Predicting the individual probability of macular hole closure following intravitreal ocriplasmin injections for vitreomacular traction release using baseline characteristics |
| Placental growth factor (PlGF) induced signalling regulates barrier properties of the retinal pigment epithelium (RPE) | |
| https://doi.org/10.1016/j.exer.2021.108608 | IL-33trap-mediated IL-33 neutralization does not exacerbate choroidal neovascularization, but fails to protect against retinal degeneration in a dry age-related macular degeneration model |
| https://doi.org/10.1158/1538-7445.am2021-1732 | Abstract 1732: Investigation of the best therapeutic approach to target CCR8 expressed on tumor regulatory T cells to boost anti-tumor immune responses |
| https://doi.org/10.1007/s10928-021-09773-w | Systemic exposure following intravitreal administration of therapeutic agents: an integrated pharmacokinetic approach. 1. THR-149 |
| https://doi.org/10.1136/bjophthalmol-2021-319500 | Resolution of outer retinal abnormalities in eyes with vitreomacular traction without macular hole in the OASIS trial |
| https://doi.org/10.1101/2021.12.24.474088 | Anticancer immunotherapies transition postcapillary venules into high-endothelial venules that generate TCF1+ T lymphocyte niches through a feed-forward loop |
| https://doi.org/10.7202/045793ar | Le musée de l’Institut canadien de Montréal (1852-1882), un projet inachevé |
| https://doi.org/10.1111/j.1755-3768.2019.5063 | The potent integrin antagonist THR‐687 is a promising next‐generation drug candidate for the treatment of multifactorial retinal diseases |
| The role of placental growth factor (PlGF) in retinal pigment epithelial (RPE) barrier integrity and outer retinal integrity in geographic atrophy | |
| https://doi.org/10.2147/opth.s285464 | Retrospective Study of Ellipsoid Zone Integrity Following Treatment with Intravitreal Ocriplasmin (OZONE Study) |
| The Mouse Sodium Iodate Model Exhibits Acute Retinal Inflammation | |
| Safety of multiple intravitreal injections of ocriplasmin in subjects with non–proliferative diabetic retinopathy (NPDR): Results of the CIRCLE study. | |
| A potential role for Src during early experimental diabetic retinopathy | |
| The effect of combined PlGF and VEGF inhibition on vascular leakage and inflammation in experimental murine models | |
| https://doi.org/10.1158/2326-6074.tumimm22-a34 | Abstract A34: Therapeutic induction of High Endothelial Venules in cancer generates TCF1+ lymphocyte niches |
| https://doi.org/10.1158/1078-0432.c.6532608 | Data from A Phase I Trial of TB-403 in Relapsed Medulloblastoma, Neuroblastoma, Ewing Sarcoma, and Alveolar Rhabdomyosarcoma |
| https://doi.org/10.1158/1078-0432.c.6532608.v1 | Data from A Phase I Trial of TB-403 in Relapsed Medulloblastoma, Neuroblastoma, Ewing Sarcoma, and Alveolar Rhabdomyosarcoma |