Rega Institute for Medical Research

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Title DOI
https://doi.org/10.1093/sysbio/syy032 Posterior Summarization in Bayesian Phylogenetics Using Tracer 1.7
https://doi.org/10.1093/ve/vey016 Bayesian phylogenetic and phylodynamic data integration using BEAST 1.10
https://doi.org/10.1126/science.1261359 Structure and function of the global ocean microbiome
https://doi.org/10.1038/s41591-019-0495-2 Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study
https://doi.org/10.1038/nature18646 Human gut microbes impact host serum metabolome and insulin sensitivity
https://doi.org/10.1038/nature15766 Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota
https://doi.org/10.1126/science.1261605 Eukaryotic plankton diversity in the sunlit ocean
https://doi.org/10.1038/s41564-018-0337-x The neuroactive potential of the human gut microbiota in quality of life and depression
https://doi.org/10.1126/science.aad3369 Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity
https://doi.org/10.1038/d41573-020-00016-0 Therapeutic options for the 2019 novel coronavirus (2019-nCoV)
https://doi.org/10.1038/s41588-020-00763-1 Large-scale association analyses identify host factors influencing human gut microbiome composition
https://doi.org/10.1016/0166-0934(88)90134-6 Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds
https://doi.org/10.1074/jbc.m301403200 Functional Characterization of Human Receptors for Short Chain Fatty Acids and Their Role in Polymorphonuclear Cell Activation
https://doi.org/10.1038/s41586-021-04389-z Considerable escape of SARS-CoV-2 Omicron to antibody neutralization
https://doi.org/10.1016/j.cell.2013.06.037 Role of PFKFB3-Driven Glycolysis in Vessel Sprouting
https://doi.org/10.1016/s1055-7903(02)00326-3 An index of substitution saturation and its application
https://doi.org/10.1126/science.abh2644 Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil
https://doi.org/10.1016/j.cmi.2018.01.002 Diagnosis and management of Aspergillus diseases: executive summary of the 2017 ESCMID-ECMM-ERS guideline
https://doi.org/10.1038/nn.3318 Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways
https://doi.org/10.1128/cmr.00102-15 Approved Antiviral Drugs over the Past 50 Years
https://doi.org/10.1038/nbt.2939 Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes
https://doi.org/10.1242/dmm.017400 How informative is the mouse for human gut microbiota research?
https://doi.org/10.1074/jbc.270.45.27348 The Functional Role of the ELR Motif in CXC Chemokine-mediated Angiogenesis
https://doi.org/10.1038/s41564-017-0072-8 Enterotypes in the landscape of gut microbial community composition
https://doi.org/10.1038/nature24460 Quantitative microbiome profiling links gut community variation to microbial load
https://doi.org/10.1038/nrmicro.2017.58 The resilience of the intestinal microbiota influences health and disease
https://doi.org/10.1038/s41564-020-0771-4 Evolutionary origins of the SARS-CoV-2 sarbecovirus lineage responsible for the COVID-19 pandemic
https://doi.org/10.1038/nm731 Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1
https://doi.org/10.1128/jvi.78.12.6381-6388.2004 Clades of Adeno-Associated Viruses Are Widely Disseminated in Human Tissues
https://doi.org/10.1038/89490 CXCR4-activated astrocyte glutamate release via TNFα: amplification by microglia triggers neurotoxicity
https://doi.org/10.1136/gutjnl-2015-309618 Stool consistency is strongly associated with gut microbiota richness and composition, enterotypes and bacterial growth rates
https://doi.org/10.1126/science.1262073 Determinants of community structure in the global plankton interactome
https://doi.org/10.1016/j.cell.2021.03.028 N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2
https://doi.org/10.1007/s00705-011-1006-z Uniformity of rotavirus strain nomenclature proposed by the Rotavirus Classification Working Group (RCWG)
https://doi.org/10.1371/journal.pone.0004724 Drug Resistance Mutations for Surveillance of Transmitted HIV-1 Drug-Resistance: 2009 Update
https://doi.org/10.1016/j.jcv.2004.02.009 Antiviral drugs in current clinical use
https://doi.org/10.1080/10409230290771546 Biochemistry and Molecular Biology of Gelatinase B or Matrix Metalloproteinase-9 (MMP-9)
https://doi.org/10.1128/jvi.02257-07 Full Genome-Based Classification of Rotaviruses Reveals a Common Origin between Human Wa-Like and Porcine Rotavirus Strains and Human DS-1-Like and Bovine Rotavirus Strains
https://doi.org/10.1016/j.cell.2019.03.040 Marine DNA Viral Macro- and Microdiversity from Pole to Pole
https://doi.org/10.1016/j.cell.2021.12.018 Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches
https://doi.org/10.1038/s41586-020-2787-6 Animal models for COVID-19
https://doi.org/10.1038/nature16942 Plankton networks driving carbon export in the oligotrophic ocean
https://doi.org/10.1002/art.1780310614 Interleukin‐6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides
https://doi.org/10.1007/s00467-018-4005-4 Oxidative stress in chronic kidney disease
https://doi.org/10.1038/ismej.2015.235 Correlation detection strategies in microbial data sets vary widely in sensitivity and precision
https://doi.org/10.1016/j.cell.2018.02.044 The Human Gut Microbiome: From Association to Modulation
https://doi.org/10.1126/science.1261498 Patterns and ecological drivers of ocean viral communities
https://doi.org/10.1093/nar/gkq1028 The RNA modification database, RNAMDB: 2011 update
https://doi.org/10.1126/science.1219669 Mapping the Origins and Expansion of the Indo-European Language Family
https://doi.org/10.1038/nrd2308 Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases
https://doi.org/10.1016/s1359-6101(03)00049-2 The CC chemokine CCL20 and its receptor CCR6
https://doi.org/10.1038/s41571-019-0203-7 Navigating metabolic pathways to enhance antitumour immunity and immunotherapy
https://doi.org/10.1038/323464a0 A novel selective broad-spectrum anti-DNA virus agent
https://doi.org/10.1007/s00705-008-0155-1 Recommendations for the classification of group A rotaviruses using all 11 genomic RNA segments
https://doi.org/10.1038/nm0198-072 AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor
https://doi.org/10.1042/cs0790161 Response of Serum Interleukin-6 in Patients Undergoing Elective Surgery of Varying Severity
https://doi.org/10.1038/343470a0 Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives
https://doi.org/10.1080/10409239891204198 Concepts and Principles of O-Linked Glycosylation
https://doi.org/10.1128/aac.03011-14 Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture
https://doi.org/10.3109/10409238.2013.770819 Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9): The next decade
https://doi.org/10.1016/s0006-2952(00)00529-3 Angiogenesis: regulators and clinical applications
https://doi.org/10.1016/j.cell.2016.08.020 Domestication and Divergence of Saccharomyces cerevisiae Beer Yeasts
https://doi.org/10.2807/1560-7917.es.2020.25.9.2000178 First cases of coronavirus disease 2019 (COVID-19) in the WHO European Region, 24 January to 21 February 2020
https://doi.org/10.1093/femsre/fuy030 From hairballs to hypotheses–biological insights from microbial networks
https://doi.org/10.1016/s1359-6101(02)00045-x Macrophage inflammatory protein-1
https://doi.org/10.1021/jm00014a001 Toward Improved Anti-HIV Chemotherapy: Therapeutic Strategies for Intervention with HIV Infections
https://doi.org/10.1074/jbc.m209278200 HIV-1 Integrase Forms Stable Tetramers and Associates with LEDGF/p75 Protein in Human Cells
https://doi.org/10.1016/j.ebiom.2021.103293 Short chain fatty acids and its producing organisms: An overlooked therapy for IBD?
https://doi.org/10.1038/nrd1877 Acyclic nucleoside phosphonates: a key class of antiviral drugs
https://doi.org/10.1007/978-94-009-3353-8 Frontiers in Microbiology
https://doi.org/10.1182/blood.v96.8.2673 Neutrophil gelatinase B potentiates interleukin-8 tenfold by aminoterminal processing, whereas it degrades CTAP-III, PF-4, and GRO-α and leaves RANTES and MCP-2 intact
https://doi.org/10.1038/nrd2175 Antiviral agents active against influenza A viruses
https://doi.org/10.1016/j.bbrc.2004.08.085 In vitro inhibition of severe acute respiratory syndrome coronavirus by chloroquine
https://doi.org/10.1126/science.abd2161 Evolution and epidemic spread of SARS-CoV-2 in Brazil
https://doi.org/10.1038/nrd703 Strategies in the design of antiviral drugs
https://doi.org/10.1016/s1473-3099(07)70081-6 Human T-lymphotropic virus 1: recent knowledge about an ancient infection
https://doi.org/10.1038/s41573-023-00672-y Therapeutic strategies for COVID-19: progress and lessons learned
https://doi.org/10.1038/nature14460 Global circulation patterns of seasonal influenza viruses vary with antigenic drift
https://doi.org/10.3389/fpubh.2018.00241 Emergence of Monkeypox as the Most Important Orthopoxvirus Infection in Humans
https://doi.org/10.1016/j.canlet.2008.04.050 The role of CXC chemokines and their receptors in cancer
https://doi.org/10.1034/j.1600-0501.1996.070302.x The influence of abutment surface roughness on plaque accumulation and peri‐implant mucositis
https://doi.org/10.1093/molbev/mss243 Accurate Model Selection of Relaxed Molecular Clocks in Bayesian Phylogenetics
https://doi.org/10.1093/molbev/msw082 SpreaD3: Interactive Visualization of Spatiotemporal History and Trait Evolutionary Processes
https://doi.org/10.1126/science.abe3354 Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms
https://doi.org/10.1093/molbev/mss265 Improving Bayesian Population Dynamics Inference: A Coalescent-Based Model for Multiple Loci
https://doi.org/10.1016/j.ijantimicag.2008.10.010 Anti-HIV drugs: 25 compounds approved within 25 years after the discovery of HIV
https://doi.org/10.1128/jvi.79.3.1595-1604.2005 Complete Genomic Sequence of Human Coronavirus OC43: Molecular Clock Analysis Suggests a Relatively Recent Zoonotic Coronavirus Transmission Event
https://doi.org/10.1189/jlb.70.6.849 Modes of action of Freund's adjuvants in experimental models of autoimmune diseases
https://doi.org/10.1016/j.vetmic.2009.08.028 Zoonotic aspects of rotaviruses
https://doi.org/10.1021/acs.jmedchem.9b01828 α-Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment
https://doi.org/10.3390/pr9010071 Molecular Dynamics Simulations in Drug Discovery and Pharmaceutical Development
https://doi.org/10.1016/s0928-0987(99)00038-x Synthesis, antibacterial, antifungal and anti-HIV activities of Schiff and Mannich bases derived from isatin derivatives and N-[4-(4′-chlorophenyl)thiazol-2-yl] thiosemicarbazide
https://doi.org/10.1038/s41586-021-03807-6 SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape
https://doi.org/10.1038/s41423-020-0412-0 Neutrophil chemoattractant receptors in health and disease: double-edged swords
https://doi.org/10.1038/ncomms7673 Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature
https://doi.org/10.1084/jem.186.8.1383 Inhibition of T-tropic HIV Strains by Selective Antagonization of the Chemokine Receptor CXCR4
https://doi.org/10.1084/jem.20051342 Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis
https://doi.org/10.1189/jlb.69.6.851 Gelatinase B functions as regulator and effector in leukocyte biology
https://doi.org/10.1186/s40168-020-00857-2 Earth microbial co-occurrence network reveals interconnection pattern across microbiomes
https://doi.org/10.1016/j.molcel.2017.02.013 Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics